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![xanthine dehydrogenase Mouse Monoclonal Antibody [1C8] — image 1 of 3](https://cdn.genprice.uk/products/992/68dd1c8d061270361ea81eb4/imageurl/em1701-56.webp)
Product details
Catalog number EM1701-56
Price for EM1701-56
Size / count 100 µL
The process of metabolizing purines to a common molecule known as xanthine is an essential process for the proper shuttling of uric acid. Xanthine oxidase is a flavoprotein enzyme that coordinates molybdenum and utilizes NAD+ as an electron acceptor to catalyze the oxidation of hypoxanthine to xanthine and then to uric acid. The predominant form of this enzyme is xanthine dehydrogenase, which is a homodimer that can be converted to xanthine oxidase by sulfhydryl oxidation or proteolytic modification. Xanthine oxidase is present in species ranging from bacteria to human and is ubiquitously expressed in mammalian tissues. In the oxidase form, this enzyme is coupled to the generation of free radicals. Individuals showing marked elevation of serum xanthine oxidase is suggestive of chronic liver disease and cholestasis, which is a condition defined by hepatic obstruction. Hepatic obstruction causes bile salts, the bile pigment bilirubin, and fats to accumulate in the blood stream instead of being eliminated normally. The clinical consequences of defects in xanthine oxidase range from mild to severe and even contribute to fatal disorders.
The catalog number for xanthine dehydrogenase Mouse Monoclonal Antibody [1C8] is EM1701-56.
xanthine dehydrogenase Mouse Monoclonal Antibody [1C8] is available in the following size(s): 100 µL.
xanthine dehydrogenase Mouse Monoclonal Antibody [1C8] is currently made to order / not held in immediate stock. Contact us for lead time.
The process of metabolizing purines to a common molecule known as xanthine is an essential process for the proper shuttling of uric acid. Xanthine oxidase is a flavoprotein enzyme that coordinates molybdenum and utilizes NAD+ as an electron acceptor to catalyze the oxidation of hypoxanthine to xanth
Yes, contact us with details of your sample type, species, and intended application, and our specialists will confirm suitability or suggest an alternative from our supplier network if this isn’t the best fit.
Purity, typically assessed by SDS-PAGE, is listed on the datasheet under quality control data.
Report this to us immediately with photos and your order reference. Our specialists will assess whether the product is still usable given the cold-chain interruption, and will arrange a replacement or credit if it isn’t.
