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Product details

PTBP1 Mouse Monoclonal Antibody [9A1]

Catalog number EM1701-63

Price for EM1701-63

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Size / count 100 µL

About this product

Plays a role in pre-mRNA splicing and in the regulation of alternative splicing events. Activates exon skipping of its own pre-mRNA during muscle cell differentiation. Binds to the polypyrimidine tract of introns. May promote RNA looping when bound to two separate polypyrimidine tracts in the same pre-mRNA. May promote the binding of U2 snRNP to pre-mRNA. Cooperates with RAVER1 to modulate switching between mutually exclusive exons during maturation of the TPM1 pre-mRNA. Represses the splicing of MAPT/Tau exon 10. In case of infection by picornaviruses, binds to the viral internal ribosome entry site (IRES) and stimulates the IRES-mediated translation.

Specifications

Catalog number
EM1701-63
Size / count
100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Product Name Alternative
57 kDa RNA binding protein PPTB 1 antibody 57 kDa RNA-binding protein PPTB-1 antibody Heterogeneous nuclear ribonucleoprotein I antibody Heterogeneous Nuclear Ribonucleoprotein Polypeptide I antibody hnRNP I antibody HNRNP-I antibody HNRNPI antibody HNRPI antibody MGC10830 antibody MGC8461 antibody Polypyrimidine tract binding protein (heterogeneous nuclear ribonucleoprotein I) antibody Polypyrimidine Tract Binding Protein 1 antibody Polypyrimidine tract binding protein antibody Polypyrimidine tract-binding protein 1 antibody pPTB antibody PTB 1 antibody PTB 2 antibody PTB 3 antibody PTB 4 antibody PTB antibody PTB T antibody PTB1 antibody PTB2 antibody PTB3 antibody PTB4 antibody PTBP 1 antibody PTBP1 antibody PTBP1_HUMAN antibody PTBT antibody RNA Binding Protein antibody
Abbreviation
PTB, hnRNP I, PTBP1, PTB
Swiss Prot
P26599 Human, Q00438 Rat
Cellular Locus
Nucleus.
Host
Mouse
Species Reactivity
Human, Rat
Immunogen
Recombinant protein within human PTBP1 aa 320-550.
Isotype
IgG2a
Conjugation
Non-conjugated
Type
Mouse monoclonal Antibody
Applications
WB, IHC-P, IF-Cell, FC
Positive Control
Jurkat cell lysate, A431 cell lysate, K562 cell lysate, A549, 293T, SW480, human kidney tissue, human tonsil tissue, rat testis tissue, human colon cancer tissue, K562.
Concentration
2 mg/mL
Dilution
WB: 1:5,000-1:10,000;IHC-P: 1:50-1:100;IF-Cell: 1:50-1:100;FC: 1:50-1:100
Purity
Protein G affinity purified.
Form
Liquid
Buffer
1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 57 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
No

Frequently Asked Questions

What is the catalog number for PTBP1 Mouse Monoclonal Antibody [9A1]?

The catalog number for PTBP1 Mouse Monoclonal Antibody [9A1] is EM1701-63.

What sizes are available for PTBP1 Mouse Monoclonal Antibody [9A1]?

PTBP1 Mouse Monoclonal Antibody [9A1] is available in the following size(s): 100 µL.

Is PTBP1 Mouse Monoclonal Antibody [9A1] in stock?

PTBP1 Mouse Monoclonal Antibody [9A1] is currently made to order / not held in immediate stock. Contact us for lead time.

What is PTBP1 Mouse Monoclonal Antibody [9A1] used for?

Plays a role in pre-mRNA splicing and in the regulation of alternative splicing events. Activates exon skipping of its own pre-mRNA during muscle cell differentiation. Binds to the polypyrimidine tract of introns. May promote RNA looping when bound to two separate polypyrimidine tracts in the same p

Is this product species cross-reactive?

Cross-reactivity data, based on available testing, is listed under the reactivity section of the datasheet. Contact us if you need reactivity confirmed for a species not listed.

Is there an additional fee for hazardous or dry ice shipping of this product?

Yes, if this product requires dry ice or is classed as hazardous for transport, the additional fee will be explicitly shown in your quotation before you confirm the order, so there are no surprise charges later.

How many freeze-thaw cycles can this product tolerate?

We recommend aliquoting the product upon receipt to avoid repeated freeze-thaw cycles, which can reduce activity and stability. This is your responsibility once the product has been delivered.

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