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Product details

BHMT Mouse Monoclonal Antibody [9E1]

Catalog number EM1701-64

Price for EM1701-64

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Size / count 100 µL

About this product

Betaine-homocysteine methyltransferase (BHMT) is a zinc-dependent cytosolic protein that catalyzes the conversion of betaine and homocysteine to dimethylglycine and methionine, respectively. BHMT is highly expressed in rat liver, and its expression is regulated by dietary methionine and choline. In humans, S-adenosylmethionine (SAM) down-regulates BHMT expression by inducing NFκB, which acts as a repressor for the BHMT gene. Lowered BHMT levels can lead to ER (endoplasmic reticulum) stress. Mutations in the gene encoding for BHMT may lead to hyperhomocysteinemia, a medical condition characterized by abnormally large amounts of homocysteine in the blood which may be a risk factor for cardiovascular and cerebrovascular diseases.

Specifications

Catalog number
EM1701-64
Size / count
100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Product Name Alternative
Betaine homocysteine methyltransferase antibody Betaine homocysteine S methyltransferase 1 antibody Betaine homocysteine S methyltransferase antibody Betaine--homocysteine S-methyltransferase 1 antibody BHMT antibody BHMT1 antibody BHMT1_HUMAN antibody EC 2.1.1.5 antibody Epididymis secretory sperm binding protein Li 61p antibody HEL S 61p antibody
Abbreviation
BHMT
Swiss Prot
Q93088 Human, 329582 Mouse, O09171 Rat
Cellular Locus
Cytoplasm.
Host
Mouse
Species Reactivity
Human, Mouse, Rat
Immunogen
Recombinant protein with Human BHMT aa 250-406 / 406.
Isotype
IgG1
Conjugation
Non-conjugated
Type
Mouse monoclonal Antibody
Applications
WB, IHC-P, IF-Cell, FC
Positive Control
Human liver tissue lysate, human kidney tissue lysate, human kidney tissue, mouse kidney tissue, rat kidney tissue, SiHa, HepG2.
Concentration
2 mg/mL
Dilution
WB: 1:1,000-1:20,000 ;IF-Cell: 1:50 ;IHC-P: 1:2,000 ;FC: 1:50-1:100
Purity
Protein G affinity purified.
Form
Liquid
Buffer
1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 45 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
No

Frequently Asked Questions

What is the catalog number for BHMT Mouse Monoclonal Antibody [9E1]?

The catalog number for BHMT Mouse Monoclonal Antibody [9E1] is EM1701-64.

What sizes are available for BHMT Mouse Monoclonal Antibody [9E1]?

BHMT Mouse Monoclonal Antibody [9E1] is available in the following size(s): 100 µL.

Is BHMT Mouse Monoclonal Antibody [9E1] in stock?

BHMT Mouse Monoclonal Antibody [9E1] is currently made to order / not held in immediate stock. Contact us for lead time.

What is BHMT Mouse Monoclonal Antibody [9E1] used for?

Betaine-homocysteine methyltransferase (BHMT) is a zinc-dependent cytosolic protein that catalyzes the conversion of betaine and homocysteine to dimethylglycine and methionine, respectively. BHMT is highly expressed in rat liver, and its expression is regulated by dietary methionine and choline. In

Is this product animal-origin-free?

Animal-origin-free status, where applicable, is noted on the datasheet under formulation details.

Does this product need any special customs documentation to be imported to my country?

If you’re outside the EU, UK, or USA, you’re responsible for customs clearance and any related taxes or fees. We provide the standard import documents, such as the Commercial Invoice, Packing List, and Airway Bill, in advance, so let us know early if your customs office needs anything additional for this specific product.

What buffer is this product supplied in?

The formulation or storage buffer is listed on the product datasheet. If you require a carrier-free or custom formulation, contact us before ordering, as this may involve a made-to-order production timeline.

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