Glucocorticoid Receptor alpha Mouse Monoclonal Antibody [3F1] — image 1 of 3

Product details

Glucocorticoid Receptor alpha Mouse Monoclonal Antibody [3F1]

Catalog number EM1701-65

Price for EM1701-65

Size / count 100 µL

About this product

The glucocorticoid receptor (GR) is a ubiquitously expressed transcription factor that mediates the effects of glucocorticoids. The most abundant isoform is GR α. GR induces or represses the expression of genes in response to glucocorticoids, mediating such processes as apoptosis, cell growth and differentiation. A significant class of genes suppressed by GR is controlled by the transcription factor AP-1. GR has also been shown to be the limiting factor in the induction of gene expression by glucocorticoids. It has been revealed that GR forms a complex with HSP 90, rendering the non-ligand bound receptor transcriptionally inactive. More importantly, mutant GRs lacking the signaling domain remain constitutively active.

Specifications

Catalog number: EM1701-65
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Product Name Alternative: GCCR antibody GCR antibody Glucocorticoid receptor alpha isoform antibody Glucocorticoid receptor antibody GR antibody GRL antibody NR3C1 antibody Nuclear receptor subfamily 3 group C member 1 antibody
Abbreviation: GR, NR3C1, GRL
Swiss Prot: P04150 Human
Cellular Locus: Nucleus. Cytoskeleton. Mitochondrion.
Host: Mouse
Species Reactivity: Human
Immunogen: Recombinant full length protein corresponding to Human Glucocorticoid Receptor alpha.
Isotype: IgG2a
Conjugation: Non-conjugated
Type: Mouse monoclonal Antibody
Applications: WB, IF-Cell, IHC-P, FC
Positive Control: SiHa cell lysate, A549 cell lysate, Hela, human spleen tissue, human breast carcinoma tissue, A549.
Concentration: 2 mg/mL
Dilution: WB: 1:1,000-1:5,000;IF-Cell:1:50-1:200;IHC-P: 1:50-1:200;FC: 1:50-1:100
Purity: Protein G affinity purified.
Form: Liquid
Buffer: 1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight: Predicted band size: 86 kDa
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody: No

Frequently Asked Questions

What is the catalog number for Glucocorticoid Receptor alpha Mouse Monoclonal Antibody [3F1]?

The catalog number for Glucocorticoid Receptor alpha Mouse Monoclonal Antibody [3F1] is EM1701-65.

What sizes are available for Glucocorticoid Receptor alpha Mouse Monoclonal Antibody [3F1]?

Glucocorticoid Receptor alpha Mouse Monoclonal Antibody [3F1] is available in the following size(s): 100 µL.

Is Glucocorticoid Receptor alpha Mouse Monoclonal Antibody [3F1] in stock?

Glucocorticoid Receptor alpha Mouse Monoclonal Antibody [3F1] is currently made to order / not held in immediate stock. Contact us for lead time.

What is Glucocorticoid Receptor alpha Mouse Monoclonal Antibody [3F1] used for?

What expression system was used for this recombinant protein?

The expression system, such as E. coli, HEK293, or insect cells, is listed on the datasheet under production details, which can affect post-translational modifications relevant to your application.

Can I return this product if I ordered the wrong one?

As a consumer, you have a 14-day right of withdrawal from receipt under EU consumer protection law, submitted via our withdrawal/cancellation request form. Note this applies to unused, undamaged products, and doesn’t override the expiry/storage conditions on performance-based claims.

Is this product tested for endotoxin levels?

Endotoxin testing status is noted on the datasheet where applicable, particularly for recombinant proteins intended for cell-based or functional assays. If this isn’t listed and you need confirmation, contact support with the catalogue number.