Glucocorticoid Receptor alpha Mouse Monoclonal Antibody [3F2] — image 1 of 3

Product details

Glucocorticoid Receptor alpha Mouse Monoclonal Antibody [3F2]

Catalog number EM1701-66

Price for EM1701-66

Size / count 100 µL

About this product

The glucocorticoid receptor (GR) is a ubiquitously expressed transcription factor that mediates the effects of glucocorticoids. The most abundant isoform is GR α. GR induces or represses the expression of genes in response to glucocorticoids, mediating such processes as apoptosis, cell growth and differentiation. A significant class of genes suppressed by GR is controlled by the transcription factor AP-1. GR has also been shown to be the limiting factor in the induction of gene expression by glucocorticoids. It has been revealed that GR forms a complex with HSP 90, rendering the non-ligand bound receptor transcriptionally inactive. More importantly, mutant GRs lacking the signaling domain remain constitutively active.

Specifications

Catalog number: EM1701-66
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Product Name Alternative: GCCR antibody GCR antibody Glucocorticoid receptor alpha isoform antibody Glucocorticoid receptor antibody GR antibody GRL antibody NR3C1 antibody Nuclear receptor subfamily 3 group C member 1 antibody
Abbreviation: GR, NR3C1, GRL
Swiss Prot: P04150 Human, P06537 Mouse
Cellular Locus: Cytoplasm. Nucleus.
Host: Mouse
Species Reactivity: Human, Mouse
Immunogen: Recombinant full length protein corresponding to Human Glucocorticoid Receptor alpha.
Isotype: IgG1
Conjugation: Non-conjugated
Type: Mouse monoclonal Antibody
Applications: WB, IHC-P, FC, IF-Cell
Positive Control: SiHa cell lysate, A549 cell lysate, human spleen tissue, mouse smooth muscle tissue, A549, Hela, human breast carcinoma tissue.
Concentration: 2 mg/mL
Dilution: WB: 1:1,000-1:2,000;IHC-P: 1:50-1:200;FC: 1:50-1:100;IF-Cell: 1:50
Purity: Protein G affinity purified.
Form: Liquid
Buffer: 1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight: Predicted band size: 86 kDa
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody: No

Frequently Asked Questions

What is the catalog number for Glucocorticoid Receptor alpha Mouse Monoclonal Antibody [3F2]?

The catalog number for Glucocorticoid Receptor alpha Mouse Monoclonal Antibody [3F2] is EM1701-66.

What sizes are available for Glucocorticoid Receptor alpha Mouse Monoclonal Antibody [3F2]?

Glucocorticoid Receptor alpha Mouse Monoclonal Antibody [3F2] is available in the following size(s): 100 µL.

Is Glucocorticoid Receptor alpha Mouse Monoclonal Antibody [3F2] in stock?

Glucocorticoid Receptor alpha Mouse Monoclonal Antibody [3F2] is currently made to order / not held in immediate stock. Contact us for lead time.

What is Glucocorticoid Receptor alpha Mouse Monoclonal Antibody [3F2] used for?

What is the purity of this recombinant protein?

Purity, typically assessed by SDS-PAGE, is listed on the datasheet under quality control data.

What do I do if this product arrives with reduced ice or a damaged cold-chain package?

Report this to us immediately with photos and your order reference. Our specialists will assess whether the product is still usable given the cold-chain interruption, and will arrange a replacement or credit if it isn’t.

What host species was used to raise this antibody?

The host species used in production is listed under product specifications on the datasheet, and is relevant when selecting a compatible secondary antibody for your assay.