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Product details

NFIB / NF1B2 Mouse Monoclonal Antibody [1H2]

Catalog number EM1701-67

Price for EM1701-67

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Size / count 100 µL

About this product

NF-1, also designated CTF, consists of a family of CCAAT box binding proteins that stimulate DNA replication and activate transcription. Analysis of human NF-1 messenger RNA has revealed two forms of the NF-1 protein arising from an alternate splicing of a single NF-1 gene. NF-1 binds its consensus DNA element as a homodimer via an amino-terminal DNA binding domain, and activates transcription through a putatively novel, proline-rich, carboxy terminal transactivation domain. The NF-1 protein has been shown to recognize and bind the adenovirus type 2 promoter and activate transcription of herpes simplex virus thymidine kinase genes. The NF-1 consensus element has been found in the upstream promoter region of myriad eukaryotic genes, including that of Ha-Ras, α-globin, HSP 70, GRP 78, Histone H1, myelin basic protein and in the Xenopus laevis vitellogenin gene promoter.

Specifications

Catalog number
EM1701-67
Size / count
100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Product Name Alternative
CCAAT Box Binding Transcription Factor antibody CCAAT-box-binding transcription factor antibody CTF antibody HMGIC/NFIB antibody NF-I/B antibody NF1-B antibody NF1B antibody NF1B2 antibody NFI-B antibody NFI-RED antibody Nfib antibody NFIB_HUMAN antibody NFIB2 antibody NFIB3 antibody Nuclear factor 1 B-type antibody Nuclear factor 1/B antibody Nuclear Factor 1B antibody Nuclear Factor I B antibody Nuclear factor I/B antibody TGGCA Binding Protein antibody TGGCA-binding protein antibody TRANSCRIPTION FACTOR NFIB antibody
Abbreviation
NF1-B, Nuclear factor 1/B, CTF, NF-I/B, NFI-B, NFIB
Swiss Prot
O00712 Human, P97863 Mouse,
Cellular Locus
Nucleus.
Host
Mouse
Species Reactivity
Human, Mouse, Rat
Immunogen
Recombinant protein within Human NFIB / NF1B2 aa 1-420 / 420.
Isotype
IgG2a
Conjugation
Non-conjugated
Type
Mouse monoclonal Antibody
Applications
WB, IHC-P, IF-Cell, FC
Positive Control
SH-SY5Y cell lysates, LO-2, rat heart tissue, human colon carcinoma tissue, human prostate tissue, human pancreas tissue, mouse liver tissue, SH-SY-5Y, rat liver tissue, human breast tissue.
Concentration
2 mg/mL
Dilution
WB: 1:500-1:1,000 ;IF-Cell: 1:50-1:200 ;IHC-P: 1:50-1:1,000 ;FC: 1:50-1:100
Purity
Protein G affinity purified.
Form
Liquid
Buffer
1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 47 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
No

Frequently Asked Questions

What is the catalog number for NFIB / NF1B2 Mouse Monoclonal Antibody [1H2]?

The catalog number for NFIB / NF1B2 Mouse Monoclonal Antibody [1H2] is EM1701-67.

What sizes are available for NFIB / NF1B2 Mouse Monoclonal Antibody [1H2]?

NFIB / NF1B2 Mouse Monoclonal Antibody [1H2] is available in the following size(s): 100 µL.

Is NFIB / NF1B2 Mouse Monoclonal Antibody [1H2] in stock?

NFIB / NF1B2 Mouse Monoclonal Antibody [1H2] is currently made to order / not held in immediate stock. Contact us for lead time.

What is NFIB / NF1B2 Mouse Monoclonal Antibody [1H2] used for?

NF-1, also designated CTF, consists of a family of CCAAT box binding proteins that stimulate DNA replication and activate transcription. Analysis of human NF-1 messenger RNA has revealed two forms of the NF-1 protein arising from an alternate splicing of a single NF-1 gene. NF-1 binds its consensus

What is the isotype of this antibody?

Isotype information such as IgG1 or IgG2a is listed in the product specifications on the datasheet, relevant for selecting compatible detection reagents.

Can I get a trial-size or discounted first order of this product?

We don’t generally offer free samples, but trial discounts in exchange for feedback and validation results are almost always possible. Contact us with your intended application to arrange one.

Do you offer bulk or custom quantities of this product?

Yes. Ordering two or more units, or combining this with other products, usually qualifies for a discount depending on quantity. Contact our sales team with your required volume for a custom quote.

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