NFIB / NF1B2 Mouse Monoclonal Antibody [1H4]

About this product

NF-1, also designated CTF, consists of a family of CCAAT box binding proteins that stimulate DNA replication and activate transcription. Analysis of human NF-1 messenger RNA has revealed two forms of the NF-1 protein arising from an alternate splicing of a single NF-1 gene. NF-1 binds its consensus DNA element as a homodimer via an amino-terminal DNA binding domain, and activates transcription through a putatively novel, proline-rich, carboxy terminal transactivation domain. The NF-1 protein has been shown to recognize and bind the adenovirus type 2 promoter and activate transcription of herpes simplex virus thymidine kinase genes. The NF-1 consensus element has been found in the upstream promoter region of myriad eukaryotic genes, including that of Ha-Ras, α-globin, HSP 70, GRP 78, Histone H1, myelin basic protein and in the Xenopus laevis vitellogenin gene promoter.

Specifications

Catalog number

EM1701-68

Size / count

100 µL

Dry ice

No

Hazardous

No

Discontinued

No

CAS Number

9007-83-4

Product Name Alternative

CCAAT Box Binding Transcription Factor antibody CCAAT-box-binding transcription factor antibody CTF antibody HMGIC/NFIB antibody NF-I/B antibody NF1-B antibody NF1B antibody NF1B2 antibody NFI-B antibody NFI-RED antibody Nfib antibody NFIB_HUMAN antibody NFIB2 antibody NFIB3 antibody Nuclear factor 1 B-type antibody Nuclear factor 1/B antibody Nuclear Factor 1B antibody Nuclear Factor I B antibody Nuclear factor I/B antibody TGGCA Binding Protein antibody TGGCA-binding protein antibody TRANSCRIPTION FACTOR NFIB antibody

Abbreviation

NF1-B, Nuclear factor 1/B, CTF, NF-I/B, NFI-B, NFIB

Swiss Prot

O00712 Human, P97863 Mouse,

Cellular Locus

Nucleus.

Host

Mouse

Species Reactivity

Human, Mouse, Rat

Immunogen

Recombinant full length protein corresponding to human NFIB/NF1B2.

Isotype

IgG1

Conjugation

Non-conjugated

Type

Mouse monoclonal Antibody

Applications

WB, IHC-P, FC

Positive Control

SH-SY-5Y, rat heart tissue, human prostate tissue, human pancreas tissue, mouse liver tissue lysate.

Concentration

2 mg/mL

Dilution

WB: 1:500-1:2,000 ;IHC-P: 1:50-1:200 ;FC: 1:50-1:100

Purity

Protein G affinity purified.

Form

Liquid

Buffer

1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.

Molecular Weight

Predicted band size: 47 kDa

Storage Conditions

Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.

Recombinant Antibody

No