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Product details

Peroxiredoxin 2 Mouse Monoclonal Antibody [7F5]

Catalog number EM1701-72

Price for EM1701-72

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Size / count 100 µL

About this product

The peroxiredoxin (PRX) family comprises six antioxidant proteins, PRX I, II, III, IV, V and VI, which protect cells from reactive oxygen species (ROS) by preventing the metal-catalyzed oxidation of enzymes. The PRX proteins primarily utilize thioredoxin as the electron donor for antioxidation, although they are fairly promiscuous with regard to the hydroperoxide substrate. In addition to protection from ROS, peroxiredoxins are also involved in cell proliferation, differentiation and gene expression. PRX I, II, IV and VI show diffuse cytoplasmic localization, while PRX III and V exhibit distinct mitochondrial localization. The human PRX I gene encodes a protein that is expressed in several tissues, including liver, kidney, testis, lung and nervous system. PRX II is expressed in testis, while PRX III shows expression in lung. PRX I, II and III are overexpressed in breast cancer and may be involved in its development or progression. Upregulated protein levels of PRX I and II in Alzheimer's disease (AD) and Down syndrome (DS) indicate the involvement of PRX I and II in their pathogenesis.

Specifications

Catalog number
EM1701-72
Size / count
100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Product Name Alternative
Epididymis secretory sperm binding protein Li 2a antibody HEL S 2a antibody MGC4104 antibody Natural killer cell enhancing factor B antibody Natural killer cell-enhancing factor B antibody Natural Killer Enhancing Factor B antibody NKEF B antibody NKEF-B antibody NKEFB antibody Peroxiredoxin-2 antibody PRDX 2 antibody PRDX2 antibody PRDX2_HUMAN antibody PrP antibody PRX2 antibody PRXII antibody PTX1 antibody TDPX1 antibody Thiol Specific Antioxidant 1 antibody Thiol specific antioxidant protein antibody Thiol-specific antioxidant protein antibody Thioredoxin Dependent Peroxide Reductase 1 antibody Thioredoxin peroxidase 1 antibody Thioredoxin-dependent peroxide reductase 1 antibody Torin antibody TPX1 antibody TSA antibody
Abbreviation
NKEF-B, TSA, PRDX2, NKEFB, TDPX1
Swiss Prot
P32119 Human, Q61171 Mouse, P35704 Rat
Cellular Locus
Cytoplasm.
Host
Mouse
Species Reactivity
Human, Mouse, Rat
Immunogen
Recombinant full length protein.
Isotype
IgG1
Conjugation
Non-conjugated
Type
Mouse monoclonal Antibody
Applications
WB, IHC-P, FC
Positive Control
HEK-293 cell lysate, LNCAP cell lysate, HeLa cell lysate, SH-SY5Y cell lysate, MCF7 cell lysate, HepG2 cell lysate, rat kidney tissue, human liver carcinoma tissue, mouse kidney tissue, human breast carcinoma tissue, human thyroid carcinoma tissue, PC-3M.
Concentration
2 mg/mL
Dilution
WB: 1:1,000-1:5,000 ;IHC-P: 1:200-1:1,000 ;FC: 1:50-1:100
Purity
Protein G affinity purified.
Form
Liquid
Buffer
1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 22 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
No

Frequently Asked Questions

What is the catalog number for Peroxiredoxin 2 Mouse Monoclonal Antibody [7F5]?

The catalog number for Peroxiredoxin 2 Mouse Monoclonal Antibody [7F5] is EM1701-72.

What sizes are available for Peroxiredoxin 2 Mouse Monoclonal Antibody [7F5]?

Peroxiredoxin 2 Mouse Monoclonal Antibody [7F5] is available in the following size(s): 100 µL.

Is Peroxiredoxin 2 Mouse Monoclonal Antibody [7F5] in stock?

Peroxiredoxin 2 Mouse Monoclonal Antibody [7F5] is currently made to order / not held in immediate stock. Contact us for lead time.

What is Peroxiredoxin 2 Mouse Monoclonal Antibody [7F5] used for?

The peroxiredoxin (PRX) family comprises six antioxidant proteins, PRX I, II, III, IV, V and VI, which protect cells from reactive oxygen species (ROS) by preventing the metal-catalyzed oxidation of enzymes. The PRX proteins primarily utilize thioredoxin as the electron donor for antioxidation, alth

Is this product covered by a money-back guarantee?

Yes, we guarantee a full refund or store credit if this product arrives damaged beyond usability, or has a genuine performance issue under proper usage and storage, provided you report it immediately with evidence. Claims after the expiration date or due to improper storage after receipt are excluded.

Can this product be used for diagnostic or therapeutic purposes?

No. This product, like all items we supply, is intended for research laboratory use only and must not be used for diagnostics, therapeutics, treatment, or consumption by humans or animals.

What is the shelf life of this product?

Shelf life and expiration dates vary by product and are shown on the product listing and label. Products used beyond their expiration date are not eligible for performance-related returns or refunds, so please check the lot number and expiry before use.

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