Peroxiredoxin 6 Mouse Monoclonal Antibody [7G1]

About this product

The peroxiredoxin (PRX) family comprises six antioxidant proteins, PRX I, II, III, IV, V and VI, which protect cells from reactive oxygen species (ROS) by preventing the metal-catalyzed oxidation of enzymes. The PRX proteins primarily utilize thioredoxin as the electron donor for antioxidation, although they are fairly promiscuous with regard to the hydroperoxide substrate. In addition to protection from ROS, peroxiredoxins are also involved in cell proliferation, differentiation and gene expression. PRX I, II, IV and VI show diffuse cytoplasmic localization, while PRX III and V exhibit distinct mitochondrial localization.PRX VI, a 1-Cys peroxiredoxin (also known as antioxidant protein 2 or AOP2), is highly expressed in most tissues, particularly in epithelial cells. Localized to the cell cytosol, PRX VI functions independently of other peroxiredoxins and antioxidant proteins, specializing in antioxidant defense, lung phospholipid metabolism and protection of keratinocytes from cell death induced by reactive oxygen species.

Specifications

Catalog number

EM1701-73

Size / count

100 µL

Dry ice

No

Hazardous

No

Discontinued

No

CAS Number

9007-83-4

Product Name Alternative

1 Cys antibody 1 Cys peroxiredoxin antibody 1 Cys PRX antibody 1 cysPrx antibody 1-Cys peroxiredoxin antibody 1-Cys PRX antibody 24 kDa protein antibody 9430088D19Rik antibody AA690119 antibody Acidic calcium independent phospholipase A2 antibody Acidic calcium-independent phospholipase A2 antibody aiPLA2 antibody Antioxidant protein 2 antibody AOP2 antibody Aop2 rs3 antibody Brp 12 antibody Ciliary body glutathione peroxidase antibody CP 3 antibody EC 1.11.1.15 antibody EC 1.11.1.7 antibody EC 3.1.1. antibody Epididymis secretory sperm binding protein Li 128m antibody GPx antibody HEL S 128m antibody KIAA0106 antibody Liver 2D page spot 40 antibody Ltw4 antibody Lvtw 4 antibody MGC46173 antibody mKIAA0106 antibody Non selenium glutathione peroxidase antibody Non-selenium glutathione peroxidase antibody NSGPx antibody ORF06 antibody OTTHUMP00000032693 antibody p29 antibody Peroxiredoxin-6 antibody Peroxiredoxin6 antibody PHGPx antibody Phospholipase A2 lysosomal antibody PLA2 antibody PRDX 6 antibody Prdx5 antibody PRDX6 antibody Prdx6 rs3 antibody PRDX6_HUMAN antibody PRX antibody Red blood cells page spot 12 antibody Thiol specific antioxidant protein antibody

Abbreviation

1-Cys PRX, aiPLA2, NSGPx, PRDX6, AOP2, KIAA0106

Swiss Prot

P30041 Human

Cellular Locus

Cytoplasm. Lysosome.

Host

Mouse

Species Reactivity

Human

Immunogen

Recombinant full length protein of Human PRDX6.

Isotype

IgG1

Conjugation

Non-conjugated

Type

Mouse monoclonal Antibody

Applications

WB, IHC-P, IF-Cell, FC

Positive Control

PC-3M, K562, A431, SiHa, human liver tissue, human colon cancer tissue, human kidney tissue, human placenta tissue.

Concentration

2 mg/mL

Dilution

WB: 1:500 ;IF-Cell: 1:50-1:200 ;IHC-P: 1:100-1:400 ;FC: 1:50-1:100

Purity

Protein G affinity purified.

Form

Liquid

Buffer

1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.

Molecular Weight

Predicted band size: 25 kDa

Storage Conditions

Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.

Recombinant Antibody

No