PLGF Mouse Monoclonal Antibody [3G3] — image 1 of 3

Product details

PLGF Mouse Monoclonal Antibody [3G3]

Catalog number EM1701-88

Price for EM1701-88

Size / count 100 µL

About this product

The onset of angiogenesis is believed to be an early event in tumorigenesis and may facilitate tumor progression and metastasis. Several growth factors with angiogenic activity have been described. These include fibroblast growth factor (FGF), platelet derived growth factor (PDGF), vascular endothelial growth factor (VEGF) and placenta growth factor (PlGF). Like VEGF, several PlGF variants have been shown to arise from alternative mRNA splicings. Evidence has suggested VEGF to be an obligatory component in PlGF signaling. While VEGF homodimers and VEGF/PlGF heterodimers function as potent mediators of mitogenic and chemotactic responses in endothelial cells, PlGF homodimers are effectual only at extremely high concentrations. Indeed, many of the physiological effects attributed to VEGF may actually be a result of VEGF/PlGF. VEGF and PlGF share a common receptor, Flt-1, and may also activate Flk-1/KDR.

Specifications

Catalog number: EM1701-88
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Product Name Alternative: D12S1900 antibody Pgf antibody PGFL antibody PIGF antibody Placenta growth factor antibody Placental growth factor antibody Placental growth factor, vascular endothelial growth factor related protein antibody PlGF 2 antibody PlGF antibody PLGF_HUMAN antibody PlGF2 antibody SHGC 10760 antibody
Abbreviation: PlGF, PGF, PGFL
Swiss Prot: P49763 Human, P49764 Mouse, Q63434 Rat
Cellular Locus: Secreted.
Host: Mouse
Species Reactivity: Human, Mouse, Rat
Immunogen: Recombinant protein within human PLGF aa 1-221.
Isotype: IgG1
Conjugation: Non-conjugated
Type: Mouse monoclonal Antibody
Applications: WB, IHC-P, IF-Cell
Positive Control: JAR, LOVO, rat kidney tissue, human placenta tissue, mouse testis tissue.
Concentration: 2 mg/mL
Dilution: WB: 1:500;IF-Cell: 1:50;IHC-P: 1:50-1:200
Purity: Immunogen affinity purified.
Form: Liquid
Buffer: 1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight: Predicted band size: 25 kDa
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody: No

Frequently Asked Questions

What is the catalog number for PLGF Mouse Monoclonal Antibody [3G3]?

The catalog number for PLGF Mouse Monoclonal Antibody [3G3] is EM1701-88.

What sizes are available for PLGF Mouse Monoclonal Antibody [3G3]?

PLGF Mouse Monoclonal Antibody [3G3] is available in the following size(s): 100 µL.

Is PLGF Mouse Monoclonal Antibody [3G3] in stock?

PLGF Mouse Monoclonal Antibody [3G3] is currently made to order / not held in immediate stock. Contact us for lead time.

What is PLGF Mouse Monoclonal Antibody [3G3] used for?

What host species was used to raise this antibody?

The host species used in production is listed under product specifications on the datasheet, and is relevant when selecting a compatible secondary antibody for your assay.

What is the difference between this product and a similar catalogue number?

Differences typically involve clone, conjugate, host species, or validated applications. Compare the respective datasheets, or contact us with both catalogue numbers for a direct comparison.

Do you offer custom or private-label production of this type of product?

Yes, custom antibody development and private-label production services are available. Contact our sales team to discuss your target, timeline, and quantity requirements.