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Product details

PLGF Mouse Monoclonal Antibody [3G2]

Catalog number EM1701-90

Price for EM1701-90

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Size / count 100 µL

About this product

The onset of angiogenesis is believed to be an early event in tumorigenesis and may facilitate tumor progression and metastasis. Several growth factors with angiogenic activity have been described. These include fibroblast growth factor (FGF), platelet derived growth factor (PDGF), vascular endothelial growth factor (VEGF) and placenta growth factor (PlGF). Like VEGF, several PlGF variants have been shown to arise from alternative mRNA splicings. Evidence has suggested VEGF to be an obligatory component in PlGF signaling. While VEGF homodimers and VEGF/PlGF heterodimers function as potent mediators of mitogenic and chemotactic responses in endothelial cells, PlGF homodimers are effectual only at extremely high concentrations. Indeed, many of the physiological effects attributed to VEGF may actually be a result of VEGF/PlGF. VEGF and PlGF share a common receptor, Flt-1, and may also activate Flk-1/KDR.

Specifications

Catalog number
EM1701-90
Size / count
100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Product Name Alternative
D12S1900 antibody Pgf antibody PGFL antibody PIGF antibody Placenta growth factor antibody Placental growth factor antibody Placental growth factor, vascular endothelial growth factor related protein antibody PlGF 2 antibody PlGF antibody PLGF_HUMAN antibody PlGF2 antibody SHGC 10760 antibody
Abbreviation
PlGF, PGF, PGFL, PLGF
Swiss Prot
P49763 Human, P49764 Mouse, Q63434 Rat
Cellular Locus
Secreted.
Host
Mouse
Species Reactivity
Human, Mouse, Rat
Immunogen
Recombinant protein within human PLGF aa 1-221.
Isotype
IgG1
Conjugation
Non-conjugated
Type
Mouse monoclonal Antibody
Applications
WB, IHC-P, IF-Cell
Positive Control
JAR, HepG2, LOVO, rat kidney tissue, mouse testis tissue.
Concentration
2 mg/mL
Dilution
WB: 1:500;IF-Cell: 1:50-1:100;IHC-P: 1:50-1:200
Purity
Protein G affinity purified.
Form
Liquid
Buffer
1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 25 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
No

Frequently Asked Questions

What is the catalog number for PLGF Mouse Monoclonal Antibody [3G2]?

The catalog number for PLGF Mouse Monoclonal Antibody [3G2] is EM1701-90.

What sizes are available for PLGF Mouse Monoclonal Antibody [3G2]?

PLGF Mouse Monoclonal Antibody [3G2] is available in the following size(s): 100 µL.

Is PLGF Mouse Monoclonal Antibody [3G2] in stock?

PLGF Mouse Monoclonal Antibody [3G2] is currently made to order / not held in immediate stock. Contact us for lead time.

What is PLGF Mouse Monoclonal Antibody [3G2] used for?

The onset of angiogenesis is believed to be an early event in tumorigenesis and may facilitate tumor progression and metastasis. Several growth factors with angiogenic activity have been described. These include fibroblast growth factor (FGF), platelet derived growth factor (PDGF), vascular endothel

What is the recommended dilution for this antibody?

A recommended dilution range for each validated application is provided on the datasheet, but optimal dilution should be titrated for your specific experimental system, sample type, and detection method.

What is the recommended storage temperature after reconstitution?

Post-reconstitution storage guidance is listed on the datasheet, typically requiring aliquoting and storage at -20°C or -80°C to preserve activity.

Can this product be used in multiplex assays?

Multiplex compatibility depends on the specific product and detection panel. Contact our technical support team with details of your multiplex system for guidance before ordering.

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