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Product details

ATF6 Mouse Monoclonal Antibody [8D3]

Catalog number EM1701-94

Price for EM1701-94

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Size / count 100 µL

About this product

Transmembrane glycoprotein of the endoplasmic reticulum that functions as a transcription activator and initiates the unfolded protein response (UPR) during endoplasmic reticulum stress. Cleaved upon ER stress, the N-terminal processed cyclic AMP-dependent transcription factor ATF-6 alpha translocates to the nucleus where it activates transcription of genes involved in the UPR. Binds DNA on the 5'-CCAC[GA]-3'half of the ER stress response element (ERSE) (5'-CCAAT-N9-CCAC[GA]-3') and of ERSE II (5'-ATTGG-N-CCACG-3'). Binding to ERSE requires binding of NF-Y to ERSE. Could also be involved in activation of transcription by the serum response factor. May play a role in foveal development and cone function in the retina.

Specifications

Catalog number
EM1701-94
Size / count
100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Product Name Alternative
Activating transcription factor 6 alpha antibody Activating transcription factor 6 antibody ATF 6 antibody ATF6 alpha antibody ATF6 antibody ATF6-alpha antibody ATF6A antibody ATF6A_HUMAN antibody cAMP dependent transcription factor ATF 6 alpha antibody cAMP-dependent transcription factor ATF-6 alpha antibody Cyclic AMP dependent transcription factor ATF 6 alpha antibody DKFZp686P2194 antibody ESTM49 antibody FLJ21663 antibody Processed cyclic AMP dependent transcription factor ATF 6 alpha antibody Processed cyclic AMP-dependent transcription factor ATF-6 alpha antibody
Abbreviation
cAMP-dependent transcription factor ATF-6 alpha, ATF6-alpha, ATF6
Swiss Prot
P18850 Human, F6VAN0 Mouse, G3V909 Rat
Cellular Locus
Endoplasmic reticulum. Nucleus.
Host
Mouse
Species Reactivity
Human, Mouse, Rat
Immunogen
Recombinant protein within Human ATF6 aa 1-670 / 670.
Isotype
IgG1
Conjugation
Non-conjugated
Type
Mouse monoclonal Antibody
Applications
WB, IF-Cell
Positive Control
HeLa cell lysate, Jurkat cell lysate, RAW264.7 cell lysate, PC-12 cell lysate, mouse brain tissue lysate, HeLa, mouse kidney tissue lysate, rat brain tissue, human placenta tissue, mouse testis tissue, HepG2.
Concentration
2 mg/mL
Dilution
WB: 1:500-1:5,000 ;IF-Cell: 1:100
Purity
Protein G affinity purified.
Form
Liquid
Buffer
1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 75 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
No

Frequently Asked Questions

What is the catalog number for ATF6 Mouse Monoclonal Antibody [8D3]?

The catalog number for ATF6 Mouse Monoclonal Antibody [8D3] is EM1701-94.

What sizes are available for ATF6 Mouse Monoclonal Antibody [8D3]?

ATF6 Mouse Monoclonal Antibody [8D3] is available in the following size(s): 100 µL.

Is ATF6 Mouse Monoclonal Antibody [8D3] in stock?

ATF6 Mouse Monoclonal Antibody [8D3] is currently made to order / not held in immediate stock. Contact us for lead time.

What is ATF6 Mouse Monoclonal Antibody [8D3] used for?

Transmembrane glycoprotein of the endoplasmic reticulum that functions as a transcription activator and initiates the unfolded protein response (UPR) during endoplasmic reticulum stress. Cleaved upon ER stress, the N-terminal processed cyclic AMP-dependent transcription factor ATF-6 alpha translocat

What is the shelf life of this product?

Shelf life and expiration dates vary by product and are shown on the product listing and label. Products used beyond their expiration date are not eligible for performance-related returns or refunds, so please check the lot number and expiry before use.

What expression system was used for this recombinant protein?

The expression system, such as E. coli, HEK293, or insect cells, is listed on the datasheet under production details, which can affect post-translational modifications relevant to your application.

Can I return this product if I ordered the wrong one?

As a consumer, you have a 14-day right of withdrawal from receipt under EU consumer protection law, submitted via our withdrawal/cancellation request form. Note this applies to unused, undamaged products, and doesn’t override the expiry/storage conditions on performance-based claims.

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