Osteoprotegerin Mouse Monoclonal Antibody [9C1] — image 1 of 3

Product details

Osteoprotegerin Mouse Monoclonal Antibody [9C1]

Catalog number EM1701-98

Price for EM1701-98

Size / count 100 µL

About this product

Bone morphogenesis and remodeling involve the formation of bone from osteoblasts and the resorption of bone by osteoclasts. The cytokine osteoprotegerin (OPG), also designated osteoclastogenesis inhibitory factor (OCIF), is known to inhibit osteoclast formation. A secreted glycoprotein, OPG is a member of the TNF receptor family that increases bone density and volume. OPG is thought to inhibit osteoclastogenesis by disrupting the cell-to-cell signaling between osteoblastic stromal cells and osteoclast progenitors. OPG is known to bind to TRAIL, a death domain-containing protein, and to inhibit TRAIL apoptosis in Jurkat cells. OPG also binds to osteoclast differentiation factor (ODF), also known as TRANCE/RANKL, a membrane-bound protein belonging to the TNF ligand family. Both TNFα and TNFβ upregulate OPG expression, while the bone resorbing agent prostaglandin E2 downregulates OPG.

Specifications

Catalog number: EM1701-98
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Product Name Alternative: MGC29565 antibody OCIF antibody OPG antibody Osteoclastogenesis inhibitory factor antibody Osteoprotegerin antibody PDB5 antibody TNF receptor superfamily member 11b antibody TNFRSF 11B antibody TNFRSF11B antibody TR 1 antibody TR1 antibody TR11B_HUMAN antibody Tumor necrosis factor receptor superfamily member 11B antibody
Abbreviation: TNFRSF11B, OCIF, OPG
Swiss Prot: O00300 Human, O08712 Mouse, O08727 Rat
Cellular Locus: Secreted.
Host: Mouse
Species Reactivity: Human, Mouse, Rat
Immunogen: Recombinant protein within Human Osteoprotegerin aa 1-401 / 401.
Isotype: IgG1
Conjugation: Non-conjugated
Type: Mouse monoclonal Antibody
Applications: WB, IF-Cell, IHC-P
Positive Control: MG-63 cell lysate, human liver tissue lysate, mouse kidney tissue lysate, rat heart tissue lysate, 293, rat lung tissue, human liver intestine tissue, human kidney tissue, human small intestine tissue.
Concentration: 2 mg/mL
Dilution: WB: 1:500-1:2,000 ;IF-Cell: 1:50-1:200 ;IHC-P: 1:50-1:200
Purity: Protein G affinity purified.
Form: Liquid
Buffer: 1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight: Predicted band size: 46 kDa
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody: No

Frequently Asked Questions

What is the catalog number for Osteoprotegerin Mouse Monoclonal Antibody [9C1]?

The catalog number for Osteoprotegerin Mouse Monoclonal Antibody [9C1] is EM1701-98.

What sizes are available for Osteoprotegerin Mouse Monoclonal Antibody [9C1]?

Osteoprotegerin Mouse Monoclonal Antibody [9C1] is available in the following size(s): 100 µL.

Is Osteoprotegerin Mouse Monoclonal Antibody [9C1] in stock?

Osteoprotegerin Mouse Monoclonal Antibody [9C1] is currently made to order / not held in immediate stock. Contact us for lead time.

What is Osteoprotegerin Mouse Monoclonal Antibody [9C1] used for?

What is the difference between this product and a similar catalogue number?

Differences typically involve clone, conjugate, host species, or validated applications. Compare the respective datasheets, or contact us with both catalogue numbers for a direct comparison.

Do you offer custom or private-label production of this type of product?

Yes, custom antibody development and private-label production services are available. Contact our sales team to discuss your target, timeline, and quantity requirements.

What is the immunogen used to generate this antibody?

Immunogen or antigen details used to raise this antibody are listed on the product datasheet under immunogen information.