Calpain 1 Mouse Monoclonal Antibody [2A1] — image 1 of 3

Product details

Calpain 1 Mouse Monoclonal Antibody [2A1]

Catalog number EM1801-02

Price for EM1801-02

Size / count 100 µL

About this product

Calpain 1 (large subunit), also designated µ-calpain, is an intracellular calcium-dependent protease that cleaves cyto-skeletal and submembranous proteins. Calpains are nonlysosomal, calcium-activated intracellular cysteine proteases. Calpains mediate specific Ca2+-dependent processes including cell fusion, mitosis and meiosis. Calpains are heterodimers of a small regulatory subunit and one of three large catalytic subunits, designated Calpain 1 (large subunit), Calpain 2 and Calpain p94. Calpastatin regulates Calpain by inhibiting both the proteolytic activity of Calpain and its binding to membranes. Calpastatin exists in two types, tissue type and erythrocyte type, resulting from both alternative splicing and proteolytic processing. Calpain-1 co-localizes with human leukocyte antigen-DR (HLA-DR) on activated microglia in the aging brain. Calpain influences the process of spermatogenesis and the events preceding fertilization, such as the acrosome reaction.

Specifications

Catalog number: EM1801-02
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Product Name Alternative: Ca2 activated neutral protease antibody Calcium activated neutral proteinase antibody Calcium activated neutral proteinase small subunit antibody Calcium dependent protease small subunit 1 antibody Calcium dependent protease small subunit antibody Calcium-activated neutral proteinase 1 antibody Calpain 1 antibody Calpain 1 large subunit antibody Calpain 1, (mu/I) large subunit antibody Calpain mu type antibody Calpain mu-type antibody Calpain regulatory subunit antibody Calpain small subunit 1 antibody Calpain, large polypeptide L1 antibody Calpain-1 catalytic subunit antibody Calpain-1 large subunit antibody CAN1_HUMAN antibody CANP 1 antibody CANP antibody CANP small subunit antibody CANP1 antibody CANPL 1 antibody CANPL1 antibody CAPN 1 antibody CAPN1 antibody Cell proliferation inducing protein 30 antibody Cell proliferation-inducing gene 30 protein antibody Micromolar Calpain antibody Micromolar-calpain antibody Mu Calpain antibody muCANP antibody muCL antibody
Abbreviation: CANP 1, muCANP, CAPN1, CANPL1, PIG30
Swiss Prot: P07384 Human, P97571 Rat
Cellular Locus: Plasma membrane.
Host: Mouse
Species Reactivity: Human, Rat
Immunogen: Recombinant protein within Human Calpain 1 aa 1-714 / 714.
Isotype: IgG1
Conjugation: Non-conjugated
Type: Mouse monoclonal Antibody
Applications: IHC-P, FC
Positive Control: Rat testis tissue, human colon cancer tissue, human spleen tissue, A431.
Concentration: 2 mg/mL
Dilution: IHC-P: 1:50-1:200 ;FC: 1:50-1:100
Purity: Protein G affinity purified.
Form: Liquid
Buffer: 1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight: Predicted band size: 82 kDa
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody: No

Frequently Asked Questions

What is the catalog number for Calpain 1 Mouse Monoclonal Antibody [2A1]?

The catalog number for Calpain 1 Mouse Monoclonal Antibody [2A1] is EM1801-02.

What sizes are available for Calpain 1 Mouse Monoclonal Antibody [2A1]?

Calpain 1 Mouse Monoclonal Antibody [2A1] is available in the following size(s): 100 µL.

Is Calpain 1 Mouse Monoclonal Antibody [2A1] in stock?

Calpain 1 Mouse Monoclonal Antibody [2A1] is currently made to order / not held in immediate stock. Contact us for lead time.

What is Calpain 1 Mouse Monoclonal Antibody [2A1] used for?

Is this product species cross-reactive?

Cross-reactivity data, based on available testing, is listed under the reactivity section of the datasheet. Contact us if you need reactivity confirmed for a species not listed.

Is there an additional fee for hazardous or dry ice shipping of this product?

Yes, if this product requires dry ice or is classed as hazardous for transport, the additional fee will be explicitly shown in your quotation before you confirm the order, so there are no surprise charges later.

How many freeze-thaw cycles can this product tolerate?

We recommend aliquoting the product upon receipt to avoid repeated freeze-thaw cycles, which can reduce activity and stability. This is your responsibility once the product has been delivered.