Calpain 1 Mouse Monoclonal Antibody [2A2] — image 1 of 3

Product details

Calpain 1 Mouse Monoclonal Antibody [2A2]

Catalog number EM1801-03

Price for EM1801-03

Size / count 100 µL

About this product

Calpain 1 (large subunit), also designated µ-calpain, is an intracellular calcium-dependent protease that cleaves cyto-skeletal and submembranous proteins. Calpains are nonlysosomal, calcium-activated intracellular cysteine proteases. Calpains mediate specific Ca2+-dependent processes including cell fusion, mitosis and meiosis. Calpains are heterodimers of a small regulatory subunit and one of three large catalytic subunits, designated Calpain 1 (large subunit), Calpain 2 and Calpain p94. Calpastatin regulates Calpain by inhibiting both the proteolytic activity of Calpain and its binding to membranes. Calpastatin exists in two types, tissue type and erythrocyte type, resulting from both alternative splicing and proteolytic processing. Calpain-1 co-localizes with human leukocyte antigen-DR (HLA-DR) on activated microglia in the aging brain. Calpain influences the process of spermatogenesis and the events preceding fertilization, such as the acrosome reaction.

Specifications

Catalog number: EM1801-03
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Product Name Alternative: Ca2 activated neutral protease antibody Calcium activated neutral proteinase antibody Calcium activated neutral proteinase small subunit antibody Calcium dependent protease small subunit 1 antibody Calcium dependent protease small subunit antibody Calcium-activated neutral proteinase 1 antibody Calpain 1 antibody Calpain 1 large subunit antibody Calpain 1, (mu/I) large subunit antibody Calpain mu type antibody Calpain mu-type antibody Calpain regulatory subunit antibody Calpain small subunit 1 antibody Calpain, large polypeptide L1 antibody Calpain-1 catalytic subunit antibody Calpain-1 large subunit antibody CAN1_HUMAN antibody CANP 1 antibody CANP antibody CANP small subunit antibody CANP1 antibody CANPL 1 antibody CANPL1 antibody CAPN 1 antibody CAPN1 antibody Cell proliferation inducing protein 30 antibody Cell proliferation-inducing gene 30 protein antibody Micromolar Calpain antibody Micromolar-calpain antibody Mu Calpain antibody muCANP antibody muCL antibody
Abbreviation: CANP 1, muCANP, CAPN1, CANPL1, PIG30
Swiss Prot: P07384 Human, O35350 Mouse, P97571 Rat
Cellular Locus: Cell membrane, Cytoplasm, Membrane.
Host: Mouse
Species Reactivity: Human, Mouse, Rat
Immunogen: Recombinant protein within Human Calpain 1 aa 1-714 / 714.
Isotype: IgM
Conjugation: Non-conjugated
Type: Mouse monoclonal Antibody
Applications: IF-Cell, IHC-P, FC
Positive Control: Rat testis tissue, human spleen tissue, human colon cancer tissue, human kidney tissue, mouse fallopian tubes tissue, A431, SiHa.
Concentration: 2 mg/mL
Dilution: IF-Cell: 1:50-1:200;IHC-P: 1:50-1:200;FC: 1:50-1:100
Purity: Protein L affinity purified.
Form: Liquid
Buffer: 1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight: Predicted band size: 82 kDa
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody: No

Frequently Asked Questions

What is the catalog number for Calpain 1 Mouse Monoclonal Antibody [2A2]?

The catalog number for Calpain 1 Mouse Monoclonal Antibody [2A2] is EM1801-03.

What sizes are available for Calpain 1 Mouse Monoclonal Antibody [2A2]?

Calpain 1 Mouse Monoclonal Antibody [2A2] is available in the following size(s): 100 µL.

Is Calpain 1 Mouse Monoclonal Antibody [2A2] in stock?

Calpain 1 Mouse Monoclonal Antibody [2A2] is currently made to order / not held in immediate stock. Contact us for lead time.

What is Calpain 1 Mouse Monoclonal Antibody [2A2] used for?

Is this product animal-origin-free?

Animal-origin-free status, where applicable, is noted on the datasheet under formulation details.

Does this product need any special customs documentation to be imported to my country?

If you’re outside the EU, UK, or USA, you’re responsible for customs clearance and any related taxes or fees. We provide the standard import documents, such as the Commercial Invoice, Packing List, and Airway Bill, in advance, so let us know early if your customs office needs anything additional for this specific product.

What buffer is this product supplied in?

The formulation or storage buffer is listed on the product datasheet. If you require a carrier-free or custom formulation, contact us before ordering, as this may involve a made-to-order production timeline.