NQO1 Mouse Monoclonal Antibody [13A1] — image 1 of 3

Product details

NQO1 Mouse Monoclonal Antibody [13A1]

Catalog number EM1801-21

Price for EM1801-21

Size / count 100 µL

About this product

NQO1, a 274 amino acid protein, is ubiquitously expressed, but the expression level varies among tissues. NQO1 gene expression is coordinately induced in response to xenobiotics, antioxidants, heavy metals and radiation. The antioxidant response element (ARE) in the NQO1 gene promoter is essential for expression and coordinated induction of NQO1. ARE activation by tert-butylhydroquinone is dependent on PI3-kinase, which lies upstream of Nrf2. Nrf2, c-Jun, Nrf1, Jun-B and Jun-D bind to the ARE and regulate expression and induction of NQO1 gene. Maf-Maf homodimers and possibly Maf-Nrf2 heterodimers play a role in negative regulation of ARE-mediated transcription, but Maf-Nrf1 heterodimers fail to bind with the NQO1 gene ARE and do not repress NQO1 transcription.

Specifications

Catalog number: EM1801-21
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Product Name Alternative: Azoreductase antibody Cytochrome b 5 reductase antibody DHQU antibody DIA 4 antibody DIA4 antibody Diaphorase (NADH/NADPH) (cytochrome b 5 reductase) antibody Diaphorase (NADH/NADPH) antibody Diaphorase 4 antibody Dioxin inducible 1 antibody DT diaphorase antibody DT-diaphorase antibody DTD antibody Menadione reductase antibody NAD (P)H dehydrogenase [quinone] 1 antibody NAD (P)H dehydrogenase quinone 1 antibody NAD (P)H menadione oxidoreductase 1 dioxin inducible antibody NAD (P)H quinone dehydrogenase 1 antibody NAD (P)H: menadione oxidoreductase 1 dioxin inducible 1 antibody NAD (P)H:menadione oxidoreductase 1 antibody NAD (P)H:Quinone acceptor oxidoreductase type 1 antibody NAD (P)H:quinone oxidoreductase 1 antibody NAD (P)H:quinone oxireductase antibody NMOR 1 antibody NMOR I antibody NMOR1 antibody NMORI antibody NQO 1 antibody NQO1 antibody NQO1_HUMAN antibody Phylloquinone reductase antibody QR 1 antibody QR1 antibody Quinone reductase 1 antibody
Abbreviation: DTD, QR1, NQO1, DIA4, NMOR1
Swiss Prot: P15559 Human, P05982 Rat
Cellular Locus: Cytoplasm.
Host: Mouse
Species Reactivity: Human, Rat
Immunogen: Recombinant protein within Human NQO1 aa 1-274 / 274.
Isotype: IgG2b
Conjugation: Non-conjugated
Type: Mouse monoclonal Antibody
Applications: WB
Positive Control: A549 cell lysate, SiHa cell lysate, HepG2 cell lysate, MCF7 cell lysate, HeLa cell lysate.
Concentration: 2 mg/mL
Dilution: WB: 1:2,000
Purity: Immunogen affinity purified.
Form: Liquid
Buffer: 1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight: Predicted band size: 31 kDa
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody: No

Frequently Asked Questions

What is the catalog number for NQO1 Mouse Monoclonal Antibody [13A1]?

The catalog number for NQO1 Mouse Monoclonal Antibody [13A1] is EM1801-21.

What sizes are available for NQO1 Mouse Monoclonal Antibody [13A1]?

NQO1 Mouse Monoclonal Antibody [13A1] is available in the following size(s): 100 µL.

Is NQO1 Mouse Monoclonal Antibody [13A1] in stock?

NQO1 Mouse Monoclonal Antibody [13A1] is currently made to order / not held in immediate stock. Contact us for lead time.

What is NQO1 Mouse Monoclonal Antibody [13A1] used for?

How many freeze-thaw cycles can this product tolerate?

We recommend aliquoting the product upon receipt to avoid repeated freeze-thaw cycles, which can reduce activity and stability. This is your responsibility once the product has been delivered.

Is antigen retrieval required for IHC with this antibody?

Recommended antigen retrieval methods, where applicable, are listed on the datasheet under the IHC protocol section.

What temperature does this product ship at?

Shipping temperature is chosen based on the product’s stability needs, ranging from ambient to dry ice, and is indicated on the product page. Any related shipping fee is shown clearly in your quotation.