Cytokeratin 5+6 Mouse Monoclonal Antibody [A2B2] — image 1 of 3

Product details

Cytokeratin 5+6 Mouse Monoclonal Antibody [A2B2]

Catalog number EM1901-08

Price for EM1901-08

Size / count 100 µL

About this product

The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. As many as six of this type II cytokeratin (KRT6) have been identified; the multiplicity of the genes is attributed to successive gene duplication events. The genes are expressed with family members KRT16 and/or KRT17 in the filiform papillae of the tongue, the stratified epithelial lining of oral mucosa and esophagus, the outer root sheath of hair follicles, and the glandular epithelia. This KRT6 gene in particular encodes the most abundant isoform. Mutations in these genes have been associated with pachyonychia congenita. In addition, peptides from the C-terminal region of the protein have antimicrobial activity against bacterial pathogens. The type II cytokeratins are clustered in a region of chromosome 12q12-q13.

Specifications

Catalog number: EM1901-08
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Product Name Alternative: 58 kDa cytokeratin antibody CK-5 antibody CK5 antibody Cytokeratin-5 antibody Cytokeratin5 antibody DDD antibody DDD1 antibody EBS2 antibody epidermolysis bullosa simplex 2 Dowling-Meara/Kobner/Weber-Cockayne types antibody K2C5_HUMAN antibody K5 antibody keratin 5 (epidermolysis bullosa simplex, Dowling-Meara/Kobner/Weber-Cockayne types) antibody Keratin 5 antibody Keratin antibody keratin complex 2, basic, gene 5 antibody keratin, type II cytoskeletal 5 antibody Keratin-5 antibody Keratin5 antibody KRT 5 antibody Krt5 antibody KRT5A antibody type II cytoskeletal 5 antibody Type-II keratin Kb5 antibody CK6 antibody CK 6A antibody CK 6B antibody CK 6C antibody CK 6D antibody CK 6E antibody CK-6B antibody CK-6C antibody CK-6E antibody Cytokeratin 6a antibody Cytokeratin 6B antibody Cytokeratin 6C antibody Cytokeratin 6D antibody Cytokeratin 6E antibody Cytokeratin-6B antibody Cytokeratin-6C antibody Cytokeratin-6E antibody K2C6C_HUMAN antibody K6a keratin antibody K6b keratin antibody K6C antibody K6c keratin antibody K6d keratin antibody K6e keratin antibody Keratin antibody Keratin K6h antibody Keratin type II cytoskeletal 6A antibody Keratin type II cytoskeletal 6B antibody Keratin type II cytoskeletal 6C antibody Keratin type II cytoskeletal 6D antibody Keratin type II cytoskeletal 6E antibody Keratin-6C antibody KRT6A antibody KRT6B antibody KRT6C antibody KRT6D antibody KRT6E antibody type II cytoskeletal 6C antibody Type-II keratin Kb12 antibody
Abbreviation: CK-6A CK-6D K6A CK-6B K6B KRT6B CK-5 K5 KRT5
Swiss Prot: P02538 Human, P04259 Human, P13647 Human, Q6P6Q2 Rat, Q4FZU2 Rat
Cellular Locus: Cytoskeleton.
Host: Mouse
Species Reactivity: Human, Rat
Immunogen: Synthetic peptide within Human Cytokeratin 5 aa 340-380.
Isotype: IgG1
Conjugation: Non-conjugated
Type: Mouse monoclonal Antibody
Applications: WB, IHC-P, FC
Positive Control: HT-29 cell lysate, A549 cell lysate, MCF7 cell lysate, HeLa cell lysate, human tonsil tissue, human skin tissue, human lung adenocarcinoma tissue, rat skin tissue, A431.
Concentration: 2 mg/mL
Dilution: WB: 1:1,000-1:5,000 ;IHC-P: 1:200-1:1,000 ;FC: 1:50-1:100
Purity: Protein A affinity purified.
Form: Liquid
Buffer: 1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight: Predicted band size: 60/62 kDa
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody: No

Frequently Asked Questions

What is the catalog number for Cytokeratin 5+6 Mouse Monoclonal Antibody [A2B2]?

The catalog number for Cytokeratin 5+6 Mouse Monoclonal Antibody [A2B2] is EM1901-08.

What sizes are available for Cytokeratin 5+6 Mouse Monoclonal Antibody [A2B2]?

Cytokeratin 5+6 Mouse Monoclonal Antibody [A2B2] is available in the following size(s): 100 µL.

Is Cytokeratin 5+6 Mouse Monoclonal Antibody [A2B2] in stock?

Cytokeratin 5+6 Mouse Monoclonal Antibody [A2B2] is currently made to order / not held in immediate stock. Contact us for lead time.

What is Cytokeratin 5+6 Mouse Monoclonal Antibody [A2B2] used for?

Does this cell line or biologic require a Material Transfer Agreement (MTA)?

Some products, including certain cell lines, plasmids, and tissue cultures, are subject to intellectual property terms and may require an MTA before we can ship. We’ll inform you in advance if this product requires one, and additional handling fees may apply.

What should I do if I need to report a performance issue with a specific lot of this product?

Provide the catalogue number, product name, lot number, and your experimental results to our technical support team. They’ll investigate and, if needed, escalate to the manufacturer, provided the product was used before expiry and stored correctly.

What is the isotype of this antibody?

Isotype information such as IgG1 or IgG2a is listed in the product specifications on the datasheet, relevant for selecting compatible detection reagents.