NM23 Mouse Monoclonal Antibody [13C1]

About this product

Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. Possesses nucleoside-diphosphate kinase, serine/threonine-specific protein kinase, geranyl and farnesyl pyrophosphate kinase, histidine protein kinase and 3'-5' exonuclease activities. Involved in cell proliferation, differentiation and development, signal transduction, G protein-coupled receptor endocytosis, and gene expression. Required for neural development including neural patterning and cell fate determination. During GZMA-mediated cell death, works in concert with TREX1. NME1 nicks one strand of DNA and TREX1 removes bases from the free 3' end to enhance DNA damage and prevent DNA end reannealing and rapid repair.

Specifications

Catalog number

EM1901-09

Size / count

100 µL

Dry ice

No

Hazardous

No

Discontinued

No

CAS Number

9007-83-4

Product Name Alternative

AWD antibody AWD, drosophila, homolog of antibody GAAD antibody Granzyme A activated DNase antibody Granzyme A-activated DNase antibody GZMA activated DNase antibody Metastasis inhibition factor NM23 antibody NB antibody NBS antibody NDK A antibody NDKA antibody NDKA_HUMAN antibody NDP kinase A antibody NDPK-A antibody NDPKA antibody NM23 antibody NM23 long variant, included antibody nm23-H1 antibody NM23-M1 antibody NM23H1B, included antibody NME/NM23 nucleoside diphosphate kinase 1 antibody Nme1 antibody NME1-NME2 spliced read-through transcript, included antibody Non-metastatic cells 1, protein (NM23A) expressed in antibody Nonmetastatic cells 1, protein expressed in antibody Nonmetastatic protein 23 antibody Nonmetastatic protein 23, homolog 1 antibody Nucleoside diphosphate kinase A antibody Tumor metastatic process-associated protein antibody

Abbreviation

NME1

Swiss Prot

P15531 Human, P15532 Mouse, Q05982 Rat

Cellular Locus

Nucleus, Cytoplasm.

Host

Mouse

Species Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide within Human NM23 aa 1-50 / 152.

Isotype

IgG1

Conjugation

Non-conjugated

Type

Mouse monoclonal Antibody

Applications

WB, IHC-P, FC, IF-Cell

Positive Control

HEK-293 cell lysate, MCF7 cell lysate, Jurkat cell lysate, HeLa cell lysate, HepG2 cell lysate, K-562 cell lysate, A549 cell lysate, Raji cell lysate, NIH/3T3 cell lysate, C6 cell lysate, mouse kidney tissue lysate, mouse liver tissue lysate, mouse brain tissue lysate, rat brain tissue lysate, rat liver tissue lysate, human liver carcinoma tissue, human thyroid tissue, human skin tissue, human breast carcinoma tissue, 293.

Concentration

2 mg/mL

Dilution

WB: 1:500-1:2,000 ;IHC-P: 1:50-1:100 ;FC: 1:50-1:100 ;IF-Cell: 1:100

Purity

Protein A affinity purified.

Form

Liquid

Buffer

1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.

Molecular Weight

Predicted band size: 17 kDa

Storage Conditions

Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.

Recombinant Antibody

No