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Product details

SERPINC1 Mouse Monoclonal Antibody [15F1]

Catalog number EM1901-11

Price for EM1901-11

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Size / count 100 µL

About this product

The protein encoded by this gene is a plasma protease inhibitor and a member of the serpin superfamily. This protein inhibits thrombin as well as other activated serine proteases of the coagulation system, and it regulates the blood coagulation cascade. The protein includes two functional domains: the heparin binding-domain at the N-terminus of the mature protein, and the reactive site domain at the C-terminus. The inhibitory activity is enhanced by the presence of heparin. More than 120 mutations have been identified for this gene, many of which are known to cause antithrombin-III deficiency. Most important serine protease inhibitor in plasma that regulates the blood coagulation cascade. AT-III inhibits thrombin, matriptase-3/TMPRSS7, as well as factors IXa, Xa and XIa. Its inhibitory activity is greatly enhanced in the presence of heparin.

Specifications

Catalog number
EM1901-11
Size / count
100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Product Name Alternative
ANT3_HUMAN antibody Antithrombin antibody Antithrombin III antibody Antithrombin-III antibody AntithrombinIII antibody AT 3 antibody AT III antibody AT3 antibody AT3D antibody ATIII antibody Heparin cofactor I antibody MGC22579 antibody Serine (or cysteine) proteinase inhibitor clade C (antithrombin) member 1 antibody Serine cysteine proteinase inhibitor clade C member 1 antibody Serine proteinase inhibitor clade C member 1 antibody Serpin C1 antibody Serpin family C member 1 antibody Serpin peptidase inhibitor clade C (antithrombin) member 1 antibody SERPINC1 antibody THPH7 antibody
Abbreviation
SERPINC1
Swiss Prot
P01008 Human, P32261 Mouse, Q5M7T5 Rat
Cellular Locus
Extracellular space or secreted.
Host
Mouse
Species Reactivity
Human, Mouse, Rat, Zebrafish
Immunogen
Recombinant protein within Human SERPINC1 aa 150-370 / 464.
Isotype
IgG1
Conjugation
Non-conjugated
Type
Mouse monoclonal Antibody
Applications
WB, IHC-P, FC
Positive Control
HL-60 cell lysates, HepG2 cell lysate, SiHa cell lysate, U937 cell lysate, zebrafish tissue lysates, rat testis tissue, human lung carcinoma tissue, human liver tissue, mouse kidney tissue, HCT116.
Concentration
2 mg/mL
Dilution
WB:1:500-1:2,000 ; ICC/ IHC-P:1:50-1:200 ; FC:1:50-1:100
Purity
Protein A affinity purified.
Form
Liquid
Buffer
1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
53 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
No

Frequently Asked Questions

What is the catalog number for SERPINC1 Mouse Monoclonal Antibody [15F1]?

The catalog number for SERPINC1 Mouse Monoclonal Antibody [15F1] is EM1901-11.

What sizes are available for SERPINC1 Mouse Monoclonal Antibody [15F1]?

SERPINC1 Mouse Monoclonal Antibody [15F1] is available in the following size(s): 100 µL.

Is SERPINC1 Mouse Monoclonal Antibody [15F1] in stock?

SERPINC1 Mouse Monoclonal Antibody [15F1] is currently made to order / not held in immediate stock. Contact us for lead time.

What is SERPINC1 Mouse Monoclonal Antibody [15F1] used for?

The protein encoded by this gene is a plasma protease inhibitor and a member of the serpin superfamily. This protein inhibits thrombin as well as other activated serine proteases of the coagulation system, and it regulates the blood coagulation cascade. The protein includes two functional domains: t

Can I request additional validation data, such as western blot images, for this product?

Additional data may be available on request. Contact our technical support team with the catalogue number and we’ll check what supporting documentation the supplier can provide.

What documentation should I request if this product is used for a regulated or intellectual-property-sensitive application?

If the product is subject to intellectual property protections, we’ll advise on any MTA or usage restrictions before shipping. Let us know your intended end use so we can confirm what’s required upfront.

Is this antibody conjugated?

Conjugation status, such as unconjugated, HRP, FITC, or biotin, is specified in the product name and confirmed on the datasheet.

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