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Product details

C7 Mouse Monoclonal Antibody [15D1]

Catalog number EM1901-14

Price for EM1901-14

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Size / count 100 µL

About this product

This gene encodes a serum glycoprotein that forms a membrane attack complex together with complement components C5b, C6, C8, and C9 as part of the terminal complement pathway of the innate immune system. Its primary task is to bind the C5bC6 complex together. This junction alters the configuration of the protein molecules, exposing a hydrophobic site on C7 that allows the C7 to insert into the phospholipid bilayer of the pathogen. The protein encoded by this gene contains a cholesterol-dependent cytolysin/membrane attack complex/perforin-like (CDC/MACPF) domain and belongs to a large family of structurally related molecules that form pores involved in host immunity and bacterial pathogenesis. This protein initiates membrane attack complex formation by binding the C5b-C6 subcomplex and inserts into the phospholipid bilayer, serving as a membrane anchor. Mutations in this gene are associated with a rare disorder called C7 deficiency.

Specifications

Catalog number
EM1901-14
Size / count
100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Product Name Alternative
C7 antibody CO7_HUMAN antibody complement component 7 antibody Complement component C7 antibody
Abbreviation
C7
Swiss Prot
P10643 Human
Cellular Locus
Secreted.
Host
Mouse
Species Reactivity
Human, Mouse, Rat
Immunogen
Recombinant protein within Human C7 aa 498-641 / 843.
Isotype
IgG1
Conjugation
Non-conjugated
Type
Mouse monoclonal Antibody
Applications
WB, IF-Cell, FC
Positive Control
HepG2 cell lysate, K562 cell lysate, HUVEC cell lysate, HepG2 cells,HCT116 cell, SHG-44 cell.
Concentration
2mg/mL
Dilution
WB:1:500-1:2,000 ;IF-Cell:1:50-1:200 ;IF-Cell/FC:1:50-1:100
Purity
Protein A affinity purified.
Form
Liquid
Buffer
1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
94 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
No

Frequently Asked Questions

What is the catalog number for C7 Mouse Monoclonal Antibody [15D1]?

The catalog number for C7 Mouse Monoclonal Antibody [15D1] is EM1901-14.

What sizes are available for C7 Mouse Monoclonal Antibody [15D1]?

C7 Mouse Monoclonal Antibody [15D1] is available in the following size(s): 100 µL.

Is C7 Mouse Monoclonal Antibody [15D1] in stock?

C7 Mouse Monoclonal Antibody [15D1] is currently made to order / not held in immediate stock. Contact us for lead time.

What is C7 Mouse Monoclonal Antibody [15D1] used for?

This gene encodes a serum glycoprotein that forms a membrane attack complex together with complement components C5b, C6, C8, and C9 as part of the terminal complement pathway of the innate immune system. Its primary task is to bind the C5bC6 complex together. This junction alters the configuration o

Do you ship this product with dry ice?

Some products, including certain cell lines and biologics, require dry ice for transportation, which carries an additional fee shown clearly in your quotation. Dry ice delivery isn’t always possible to every destination due to transit time or local restrictions, so we check feasibility in advance and you must store the goods at the correct temperature the moment they arrive.

Is this product species cross-reactive?

Cross-reactivity data, based on available testing, is listed under the reactivity section of the datasheet. Contact us if you need reactivity confirmed for a species not listed.

Is there an additional fee for hazardous or dry ice shipping of this product?

Yes, if this product requires dry ice or is classed as hazardous for transport, the additional fee will be explicitly shown in your quotation before you confirm the order, so there are no surprise charges later.

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