Cytokeratin 17 Mouse Monoclonal Antibody [A2B11] — image 1 of 3

Product details

Cytokeratin 17 Mouse Monoclonal Antibody [A2B11]

Catalog number EM1901-30

Price for EM1901-30

Size / count 100 µL

About this product

Type I keratin involved in the formation and maintenance of various skin appendages, specifically in determining shape and orientation of hair (By similarity). Required for the correct growth of hair follicles, in particular for the persistence of the anagen (growth) state (By similarity). Modulates the function of TNF-alpha in the specific context of hair cycling. Regulates protein synthesis and epithelial cell growth through binding to the adapter protein SFN and by stimulating Akt/mTOR pathway (By similarity). Involved in tissue repair. May be a marker of basal cell differentiation in complex epithelia and therefore indicative of a certain type of epithelial "stem cells". Acts as a promoter of epithelial proliferation by acting a regulator of immune response in skin: promotes Th1/Th17-dominated immune environment contributing to the development of basaloid skin tumors (By similarity). May act as an autoantigen in the immunopathogenesis of psoriasis, with certain peptide regions being a major target for autoreactive T-cells and hence causing their proliferation.

Specifications

Catalog number: EM1901-30
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Product Name Alternative: 39.1 antibody CK 17 antibody CK17 antibody CK-17 antibody Cytokeratin-17 antibody K17 antibody K1C17_HUMAN antibody Keratin 17 antibody keratin 17 epitope S1 antibody keratin 17 epitope S2 antibody keratin 17 epitope S4 antibody Keratin 17, type I antibody Keratin antibody Keratin type I cytoskeletal 17 antibody keratin, type i cytoskeletal 17 [version 1] antibody Keratin-17 antibody KRT17 antibody PC antibody PC2 antibody PCHC1 antibody type I cytoskeletal 17 antibody
Abbreviation: Keratin, type I cytoskeletal 17 39.1 Cytokeratin-17 CK-17 Keratin-17 K17
Swiss Prot: Q04695 Human
Cellular Locus: Cytoplasm.
Host: Mouse
Species Reactivity: Human
Immunogen: Synthetic peptide within Human Cytokeratin 17 aa 383-432 / 432.
Isotype: IgG1
Conjugation: Non-conjugated
Type: Mouse monoclonal Antibody
Applications: WB, IHC-P, FC
Positive Control: SiHa cell lysates, human skin tissue, human lung carcinoma tissue, SiHa cells.
Concentration: 2 mg/mL
Dilution: WB: 1:500-1:2,000 ;IHC-P: 1:50-1:200 ;FC: 1:50-1:100
Purity: Protein G affinity purified.
Form: Liquid
Buffer: 1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight: Predicted band size: 48 kDa
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody: No

Frequently Asked Questions

What is the catalog number for Cytokeratin 17 Mouse Monoclonal Antibody [A2B11]?

The catalog number for Cytokeratin 17 Mouse Monoclonal Antibody [A2B11] is EM1901-30.

What sizes are available for Cytokeratin 17 Mouse Monoclonal Antibody [A2B11]?

Cytokeratin 17 Mouse Monoclonal Antibody [A2B11] is available in the following size(s): 100 µL.

Is Cytokeratin 17 Mouse Monoclonal Antibody [A2B11] in stock?

Cytokeratin 17 Mouse Monoclonal Antibody [A2B11] is currently made to order / not held in immediate stock. Contact us for lead time.

What is Cytokeratin 17 Mouse Monoclonal Antibody [A2B11] used for?

Can this product be used for co-immunoprecipitation (Co-IP)?

Suitability for Co-IP depends on the specific antibody and is noted under validated applications on the datasheet. If it isn’t listed, contact our technical support team for guidance based on your target and sample type.

Is this kit compatible with automated liquid handling platforms?

Automation compatibility varies by kit and isn’t always listed on the datasheet. Contact our technical support team with details of your platform so we can confirm with the manufacturer.

What applications has this product been validated for?

Validated applications such as WB, ELISA, IHC, ICC, or FC are listed on the product datasheet. If you need application-specific validation data before ordering, contact our technical support team with the catalogue number.