F13A1 Mouse Monoclonal Antibody [16D1]

About this product

Hemostasis following tissue injury involves the deployment of essential plasma procoagulants (prothrombin, and factors V, VIII, IX and X), which are involved in a blood coagulation cascade leading to the formation of insoluble fibrin clots and the promotion of platelet aggregation. Coagulation factor VII (serum prothrombin conversion accelerator, proconvertin, F7, Factor VII) is a 406 amino acid, vitamin K-dependent, single chain serine protease that is synthesized in the liver and circulates as an inactive precursor. Factor IXa, factor Xa, factor XIIa, or thrombin mediated proteolytic cleavage of Factor VII at Arg152-Ile153 generates Factor VIIa, an active serine protease composed of a catalytic heavy chain disulfide linked to a light chain, containing two EGF-like domains. Coagulation factor XIII is a terminal effector in the blood coagulation cascade. Plasma factor XIII is a heterotetramer composed of two A subunits and two B subunits. The A subunits have catalytic function, and the noncatalytic B subunits may serve as plasma carrier molecules.

Specifications

Catalog number

EM1901-39

Size / count

100 µL

Dry ice

No

Hazardous

No

Discontinued

No

CAS Number

9007-83-4

Product Name Alternative

bA525O21.1 (coagulation factor XIII, A1 polypeptide) antibody Coagulation factor XIII A chain antibody Coagulation factor XIII A1 polypeptide antibody Coagulation factor XIII A1 subunit antibody Coagulation factor XIII, A polypeptide antibody Coagulation factor XIIIa antibody F13A antibody F13A_HUMAN antibody F13a1 antibody Factor XIIIA antibody Fibrin stabilizing factor, A subunit antibody Fibrinoligase antibody FSF, A subunit antibody Protein glutamine gamma glutamyltransferase A chain antibody Protein-glutamine gamma-glutamyltransferase A chain antibody TGase antibody Transglutaminase A chain antibody Transglutaminase, plasma antibody Transglutaminase. plasma antibody

Abbreviation

F13A1

Swiss Prot

P00488 Human

Cellular Locus

Secreted, cytoplasm.

Host

Mouse

Species Reactivity

Human

Immunogen

Recombinant protein within Human F13A1 aa 259-463 / 732.

Isotype

IgG2a

Conjugation

Non-conjugated

Type

Mouse monoclonal Antibody

Applications

WB, IF-Cell, IHC-P, FC

Positive Control

Human placenta tissue lysates, human placenta tissue, MCF-7, MG-63, A549.

Concentration

2 mg/mL

Dilution

WB:1:500-1:2,000;IF-Cell:1:50-1:100;IHC-P:1:200-1:1,000;FC:1:50-1:100

Purity

Protein A affinity purified.

Form

Liquid

Buffer

1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.

Molecular Weight

Predicted band size: 83 kDa

Storage Conditions

Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.

Recombinant Antibody

No