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Product details

TRIM72 Mouse Monoclonal Antibody [A1D4]

Catalog number EM1901-45

Price for EM1901-45

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Size / count 100 µL

About this product

Muscle-specific protein that plays a central role in cell membrane repair by nucleating the assembly of the repair machinery at injury sites. Specifically binds phosphatidylserine. Acts as a sensor of oxidation: upon membrane damage, entry of extracellular oxidative environment results in disulfide bond formation and homooligomerization at the injury site. This oligomerization acts as a nucleation site for recruitment of TRIM72-containing vesicles to the injury site, leading to membrane patch formation. Probably acts upstream of the Ca2+-dependent membrane resealing process. Required for transport of DYSF to sites of cell injury during repair patch formation. Regulates membrane budding and exocytosis. May be involved in the regulation of the mobility of KCNB1-containing endocytic vesicles (By similarity).

Specifications

Catalog number
EM1901-45
Size / count
100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Product Name Alternative
LOC493829 antibody Mg53 antibody Mitsugumin-53 antibody TRI72_HUMAN antibody trim72 antibody Tripartite motif containing 72 antibody Tripartite motif containing protein 72 antibody Tripartite motif-containing protein 72 antibody
Abbreviation
TRIM72
Swiss Prot
Q6ZMU5 Human, Q1XH17 Mouse, A0JPQ4 Rat
Cellular Locus
Sarcolemma, cytoplasmic vesicle membrane.
Host
Mouse
Species Reactivity
Human, Mouse, Rat
Immunogen
Recombinant protein with Human TRIM72 aa 50-150 / 477.
Isotype
IgG1
Conjugation
Non-conjugated
Type
Mouse monoclonal Antibody
Applications
WB, IHC-P, FC
Positive Control
HCT 116 cell lysate, mouse skeletal muscle tissue lysate, mouse heart tissue lysate, rat heart tissue lysate, rat skeletal muscle tissue lysate, rat skeletal muscle tissue, human pancreas tissue, A549.
Concentration
2 mg/mL
Dilution
WB:1:500-1:2,000 ;IHC-P:1:50-1:200 ;FC:1:50-1:100
Purity
Protein A affinity purified.
Form
Liquid
Buffer
1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 53 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
No

Frequently Asked Questions

What is the catalog number for TRIM72 Mouse Monoclonal Antibody [A1D4]?

The catalog number for TRIM72 Mouse Monoclonal Antibody [A1D4] is EM1901-45.

What sizes are available for TRIM72 Mouse Monoclonal Antibody [A1D4]?

TRIM72 Mouse Monoclonal Antibody [A1D4] is available in the following size(s): 100 µL.

Is TRIM72 Mouse Monoclonal Antibody [A1D4] in stock?

TRIM72 Mouse Monoclonal Antibody [A1D4] is currently made to order / not held in immediate stock. Contact us for lead time.

What is TRIM72 Mouse Monoclonal Antibody [A1D4] used for?

Muscle-specific protein that plays a central role in cell membrane repair by nucleating the assembly of the repair machinery at injury sites. Specifically binds phosphatidylserine. Acts as a sensor of oxidation: upon membrane damage, entry of extracellular oxidative environment results in disulfide

What buffer is this product supplied in?

The formulation or storage buffer is listed on the product datasheet. If you require a carrier-free or custom formulation, contact us before ordering, as this may involve a made-to-order production timeline.

What dilution range is recommended for immunohistochemistry (IHC) with this antibody?

A starting IHC dilution range is listed on the datasheet, but should be optimized for your specific tissue type and staining protocol.

Can I request a Safety Data Sheet (SDS) for this product?

Yes, safety data sheets are available for hazardous or chemically classified products and can be provided on request or downloaded from the product page.

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