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Product details

ROBO1 Mouse Monoclonal Antibody [10E2]

Catalog number EM1901-72

Price for EM1901-72

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Size / count 100 µL

About this product

Specific cells in the midline separate the left and right halves of the central nervous system and play many roles in guiding the growth cone behavior. In vertebrate spinal cord, insect abdominal nerves and nematodes, midline cells produce induced cues, such as nectins and slits, respectively, as attractants and repellents. respectively. These cells can serve as gatekeepers to prevent axons from passing through the midline and to guide the growth cone in response to the switching of lead cues beyond the crossing. One such gatherer, Robo, is an axon guidance receptor that defines a new subfamily of proteins from fruit flies to mammalian conserved Ig superfamily proteins. Robo acts as a receptor for the repellent Slit and functions in a cell-autonomous manner Non-intersecting axons express high levels of Robo and cross axons to express low levels of Robo and then reach midline and high levels of crossover. Robo1 and Robo2 are two human homologs of Drosophila megalopolis. Robo1 is also homologous to the C. elegans gene sax3, while Robo2 is homologous to zebrafish genes.

Specifications

Catalog number
EM1901-72
Size / count
100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Product Name Alternative
Deleted in U twenty twenty antibody DUTT 1 antibody DUTT1 antibody FLJ21882 antibody H Robo 1 antibody H-Robo-1 antibody hRobo 1 antibody Robo 1 antibody Robo1 antibody ROBO1_HUMAN antibody Roundabout 1 antibody Roundabout axon guidance receptor homolog 1 antibody Roundabout homolog 1 antibody Roundabout homolog1 precurser antibody Roundabout1 antibody SAX 3 antibody SAX3 antibody
Abbreviation
Deleted in U twenty twenty,H-Robo-1,Roundabout homolog 1,ROBO1
Swiss Prot
Q9Y6N7 Human, O89026 Mouse, O55005 Rat
Cellular Locus
Cell membrane, Cell projection, axon, Endoplasmic reticulum-Golgi intermediate compartment membrane, cytoplasm.
Host
Mouse
Species Reactivity
Human, Mouse, Rat
Immunogen
Recombinant protein within Human ROBO1 aa 41-286 / 1,651.
Isotype
IgG1
Conjugation
Non-conjugated
Type
Mouse monoclonal Antibody
Applications
WB, IHC-P
Positive Control
293T cell lysate, Hela cell lysate, PC-3 cell lysate, human breast tissue, human placenta tissue, mouse brain tissue, rat brain tissue.
Concentration
2 mg/mL
Dilution
WB: 1:1,000-1:5,000 ;IHC-P: 1:50-1:1,000
Purity
Protein G affinity purified.
Form
Liquid
Buffer
1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 181 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
No

Frequently Asked Questions

What is the catalog number for ROBO1 Mouse Monoclonal Antibody [10E2]?

The catalog number for ROBO1 Mouse Monoclonal Antibody [10E2] is EM1901-72.

What sizes are available for ROBO1 Mouse Monoclonal Antibody [10E2]?

ROBO1 Mouse Monoclonal Antibody [10E2] is available in the following size(s): 100 µL.

Is ROBO1 Mouse Monoclonal Antibody [10E2] in stock?

ROBO1 Mouse Monoclonal Antibody [10E2] is currently made to order / not held in immediate stock. Contact us for lead time.

What is ROBO1 Mouse Monoclonal Antibody [10E2] used for?

Specific cells in the midline separate the left and right halves of the central nervous system and play many roles in guiding the growth cone behavior. In vertebrate spinal cord, insect abdominal nerves and nematodes, midline cells produce induced cues, such as nectins and slits, respectively, as at

Does this product need any special customs documentation to be imported to my country?

If you’re outside the EU, UK, or USA, you’re responsible for customs clearance and any related taxes or fees. We provide the standard import documents, such as the Commercial Invoice, Packing List, and Airway Bill, in advance, so let us know early if your customs office needs anything additional for this specific product.

What buffer is this product supplied in?

The formulation or storage buffer is listed on the product datasheet. If you require a carrier-free or custom formulation, contact us before ordering, as this may involve a made-to-order production timeline.

What dilution range is recommended for immunohistochemistry (IHC) with this antibody?

A starting IHC dilution range is listed on the datasheet, but should be optimized for your specific tissue type and staining protocol.

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