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Product details

Cytokeratin 20 Mouse Monoclonal Antibody [A3D12]

Catalog number EM1901-96

Price for EM1901-96

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Size / count 100 µL

About this product

The protein encoded by this gene is a member of the keratin family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. The type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains. This cytokeratin is a major cellular protein of mature enterocytes and goblet cells and is specifically expressed in the gastric and intestinal mucosa. Keratin 20 is a type I cytokeratin. It is a major cellular protein of mature enterocytes and goblet cells and is specifically found in the gastric and intestinal mucosa. In immunohistochemistry, antibodies to CK20 can be used to identify a range of adenocarcinoma arising from epithelia that normally contain the CK20 protein. For example, the protein is commonly found in colorectal cancer, transitional cell carcinomas and in Merkel cell carcinoma, but is absent in lung cancer, prostate cancer, and non-mucinous ovarian cancer. It is often used in combination with antibodies to CK7 to distinguish different types of glandular tumour.

Specifications

Catalog number
EM1901-96
Size / count
100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Product Name Alternative
CK 20 antibody CK-20 antibody CK20 antibody Cytokeratin-20 antibody Cytokeratin20 antibody K1C20_HUMAN antibody K20 antibody KA20 antibody Keratin 20 antibody keratin 20, type I antibody keratin 21, rat, homolog of antibody Keratin antibody Keratin type I cytoskeletal 20 antibody Keratin-20 antibody Keratin20 antibody KRT 20 antibody KRT 21 antibody KRT20 antibody KRT21 antibody MGC35423 antibody OTTHUMP00000164518 antibody Protein IT antibody type I cytoskeletal 20 antibody
Abbreviation
KRT20
Swiss Prot
P35900 Human
Cellular Locus
Cytoplasm.
Host
Mouse
Species Reactivity
Human
Immunogen
Synthetic peptide within Human Cytokeratin 20 aa 29-78 / 424.
Isotype
IgG1
Conjugation
Non-conjugated
Type
Mouse monoclonal Antibody
Applications
WB, FC, IHC-P
Positive Control
Lovo cell lysates, human small intestine tissue, human colon carcinoma tissue, human stomach carcinoma tissue, JAR.
Concentration
2 mg/mL
Dilution
WB:1:500-1:1,000 ;FC:1:50-1:100
Purity
Protein G affinity purified.
Form
Liquid
Buffer
1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
48 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
No

Frequently Asked Questions

What is the catalog number for Cytokeratin 20 Mouse Monoclonal Antibody [A3D12]?

The catalog number for Cytokeratin 20 Mouse Monoclonal Antibody [A3D12] is EM1901-96.

What sizes are available for Cytokeratin 20 Mouse Monoclonal Antibody [A3D12]?

Cytokeratin 20 Mouse Monoclonal Antibody [A3D12] is available in the following size(s): 100 µL.

Is Cytokeratin 20 Mouse Monoclonal Antibody [A3D12] in stock?

Cytokeratin 20 Mouse Monoclonal Antibody [A3D12] is currently made to order / not held in immediate stock. Contact us for lead time.

What is Cytokeratin 20 Mouse Monoclonal Antibody [A3D12] used for?

The protein encoded by this gene is a member of the keratin family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. The type I cytokeratins consist of acidic proteins which are arrang

How should this product be stored?

Storage conditions depend on the specific reagent and are listed on the product datasheet, with most antibodies and proteins requiring -20°C unless stated otherwise. It is your responsibility to store the product correctly immediately upon receipt; damage from improper storage after delivery is not eligible for replacement.

Is this product animal-origin-free?

Animal-origin-free status, where applicable, is noted on the datasheet under formulation details.

Does this product need any special customs documentation to be imported to my country?

If you’re outside the EU, UK, or USA, you’re responsible for customs clearance and any related taxes or fees. We provide the standard import documents, such as the Commercial Invoice, Packing List, and Airway Bill, in advance, so let us know early if your customs office needs anything additional for this specific product.

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