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Product details

Lysozyme Mouse Monoclonal Antibody [A5A9]

Catalog number EM1901-99

Price for EM1901-99

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Size / count 100 µL

About this product

Lysozyme, also known as muramidase or N-acetylmuramide glycanhydrolase, is an antimicrobial enzyme produced by animals that forms part of the innate immune system. Lysozyme is a glycoside hydrolase that catalyzes the hydrolysis of 1,4-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in peptidoglycan, which is the major component of gram-positive bacterial cell wall. Lysozyme is abundant in secretions including tears, saliva, human milk, and mucus. It is also present in cytoplasmic granules of the macrophages and the polymorphonuclear neutrophils (PMNs). Large amounts of lysozyme can be found in egg white. C-type lysozymes are closely related to alpha-lactalbumin in sequence and structure, making them part of the same glycoside hydrolase family 22. In humans, the C-type lysozyme enzyme is encoded by the LYZ gene. In certain cancers (especially myelomonocytic leukemia) excessive production of lysozyme by cancer cells can lead to toxic levels of lysozyme in the blood. High lysozyme blood levels can lead to kidney failure and low blood potassium, conditions that may improve or resolve with treatment of the primary malignancy. Serum lysozyme is much less specific for diagnosis of sarcoidosis than serum angiotensin converting enzyme; however, since it is more sensitive, it is used as a marker of sarcoidosis disease activity and is suitable for disease monitoring in proven cases.

Specifications

Catalog number
EM1901-99
Size / count
100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Product Name Alternative
1 4 beta N acetylmuramidase C antibody 1 antibody 4-beta-N-acetylmuramidase C antibody EC 3.2.1.17 antibody LYSC_HUMAN antibody Lysosyme antibody Lysozyme (renal amyloidosis) antibody Lysozyme C antibody Lysozyme C precursor antibody LYZ antibody LZM antibody Renal amyloidosis antibody
Abbreviation
LYZ
Swiss Prot
P61626 Human
Cellular Locus
Secreted.
Host
Mouse
Species Reactivity
Human
Immunogen
Recombinant protein within Human Lysozyme aa 1-141 / 148.
Isotype
IgG1
Conjugation
Non-conjugated
Type
Mouse monoclonal Antibody
Applications
WB, IHC-P, FC
Positive Control
HL-60 cell lysates, human spleen tissue, human stomach cancer tissue, A549.
Concentration
2 mg/mL
Dilution
WB:1:500-1:2,000 ;IHC-P: 1:1,000 ;FC:1:50-1:100
Purity
Protein G affinity purified.
Form
Liquid
Buffer
1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 17 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
No

Frequently Asked Questions

What is the catalog number for Lysozyme Mouse Monoclonal Antibody [A5A9]?

The catalog number for Lysozyme Mouse Monoclonal Antibody [A5A9] is EM1901-99.

What sizes are available for Lysozyme Mouse Monoclonal Antibody [A5A9]?

Lysozyme Mouse Monoclonal Antibody [A5A9] is available in the following size(s): 100 µL.

Is Lysozyme Mouse Monoclonal Antibody [A5A9] in stock?

Lysozyme Mouse Monoclonal Antibody [A5A9] is currently made to order / not held in immediate stock. Contact us for lead time.

What is Lysozyme Mouse Monoclonal Antibody [A5A9] used for?

Lysozyme, also known as muramidase or N-acetylmuramide glycanhydrolase, is an antimicrobial enzyme produced by animals that forms part of the innate immune system. Lysozyme is a glycoside hydrolase that catalyzes the hydrolysis of 1,4-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosa

What should I do if I need to report a performance issue with a specific lot of this product?

Provide the catalogue number, product name, lot number, and your experimental results to our technical support team. They’ll investigate and, if needed, escalate to the manufacturer, provided the product was used before expiry and stored correctly.

What is the isotype of this antibody?

Isotype information such as IgG1 or IgG2a is listed in the product specifications on the datasheet, relevant for selecting compatible detection reagents.

Can I get a trial-size or discounted first order of this product?

We don’t generally offer free samples, but trial discounts in exchange for feedback and validation results are almost always possible. Contact us with your intended application to arrange one.

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