RAP80 Mouse Monoclonal Antibody [A1B11] — image 1 of 3

Product details

RAP80 Mouse Monoclonal Antibody [A1B11]

Catalog number EM1902-05

Price for EM1902-05

Size / count 100 µL

About this product

Ubiquitin-binding protein. Specifically recognizes and binds 'Lys-63'-linked ubiquitin. Plays a central role in the BRCA1-A complex by specifically binding 'Lys-63'-linked ubiquitinated histones H2A and H2AX at DNA lesions sites, leading to target the BRCA1-BARD1 heterodimer to sites of DNA damage at double-strand breaks (DSBs). The BRCA1-A complex also possesses deubiquitinase activity that specifically removes 'Lys-63'-linked ubiquitin on histones H2A and H2AX. Also weakly binds monoubiquitin but with much less affinity than 'Lys-63'-linked ubiquitin. May interact with monoubiquitinated histones H2A and H2B; the relevance of such results is however unclear in vivo. Does not bind Lys-48'-linked ubiquitin. May indirectly act as a transcriptional repressor by inhibiting the interaction of NR6A1 with the corepressor NCOR1.

Specifications

Catalog number: EM1902-05
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Product Name Alternative: BRCA1-A complex subunit RAP80 antibody Nuclear zinc finger protein RAP80 antibody OTTHUMP00000161441 antibody OTTHUMP00000223372 antibody OTTHUMP00000223374 antibody RAP80 antibody Receptor associated protein 80 antibody Receptor-associated protein 80 antibody Retinoid X receptor interacting protein 110 antibody Retinoid x receptor interacting protein antibody Retinoid X receptor-interacting protein 110 antibody RIP110 antibody Rxrip110 antibody Ubiquitin interaction motif containing 1 antibody Ubiquitin interaction motif containing protein 1 antibody Ubiquitin interaction motif-containing protein 1 antibody UIMC1 antibody UIMC1_HUMAN antibody X2HRIP110 antibody
Abbreviation: UIMC1
Swiss Prot: Q96RL1 Human, Q5U5Q9 Mouse, Q5PQK4 Rat
Cellular Locus: Nucleus.
Host: Mouse
Species Reactivity: Human, Mouse, Rat
Immunogen: Recombinant protein within Human RAP80 aa 330-524 / 719.
Isotype: IgG1
Conjugation: Non-conjugated
Type: Mouse monoclonal Antibody
Applications: WB, IHC-P, FC
Positive Control: Siha cell lysates, rat testis tissue, mouse testis tissue, SiHa cell.
Concentration: 2 mg/mL
Dilution: WB:1:500-1:1000 ;IHC-P:1:50-1:200 ;FC:1:50-1:100
Purity: Protein A affinity purified.
Form: Liquid
Buffer: 1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight: 80 kDa
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody: No

Frequently Asked Questions

What is the catalog number for RAP80 Mouse Monoclonal Antibody [A1B11]?

The catalog number for RAP80 Mouse Monoclonal Antibody [A1B11] is EM1902-05.

What sizes are available for RAP80 Mouse Monoclonal Antibody [A1B11]?

RAP80 Mouse Monoclonal Antibody [A1B11] is available in the following size(s): 100 µL.

Is RAP80 Mouse Monoclonal Antibody [A1B11] in stock?

RAP80 Mouse Monoclonal Antibody [A1B11] is currently made to order / not held in immediate stock. Contact us for lead time.

What is RAP80 Mouse Monoclonal Antibody [A1B11] used for?

How do I reconstitute this lyophilized product?

Reconstitution instructions, including the recommended diluent and final concentration, are provided on the datasheet. Aliquot immediately after reconstitution to avoid repeated freeze-thaw cycles.

What is the recommended incubation time for this antibody?

A suggested incubation time is provided in the recommended protocol on the datasheet, but may need adjusting depending on your sample type and detection system.

What should I check when this product first arrives?

Inspect the package immediately for transportation damage, ice loss, leakage, or breakage. Report any issues right away with photos and your order reference; our specialists will determine whether the product is still usable or needs replacing.