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Product details

CD42b Mouse Monoclonal Antibody [13G2]

Catalog number EM1902-15

Price for EM1902-15

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Size / count 100 µL

About this product

Glycoprotein Ib (GP Ib) is a platelet surface membrane glycoprotein composed of a heterodimer, an alpha chain and a beta chain, that is linked by disulfide bonds. The Gp Ib functions as a receptor for von Willebrand factor (VWF). The complete receptor complex includes noncovalent association of the alpha and beta subunits with platelet glycoprotein IX and platelet glycoprotein V. The binding of the GP Ib-IX-V complex to VWF facilitates initial platelet adhesion to vascular subendothelium after vascular injury, and also initiates signaling events within the platelet that lead to enhanced platelet activation, thrombosis, and hemostasis. This gene encodes the alpha subunit. Mutations in this gene result in Bernard-Soulier syndromes and platelet-type von Willebrand disease. The coding region of this gene is known to contain a polymophic variable number tandem repeat (VNTR) domain that is associated with susceptibility to nonarteritic anterior ischemic optic neuropathy.

Specifications

Catalog number
EM1902-15
Size / count
100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Product Name Alternative
Antigen CD42b alpha antibody BDPLT1 antibody BDPLT3 antibody BSS antibody CD 42b antibody CD42b alpha antibody CD42B antibody CD42b antigen antibody DBPLT3 antibody GLYCOCALICIN antibody Glycoprotein Ib (platelet) alpha polypeptide antibody Glycoprotein Ibalpha antibody GP Ib alpha antibody GP1B antibody GP1BA antibody GPIb alpha antibody GPIbA antibody MGC34595 antibody Platelet glycoprotein Ib alpha chain antibody Platelet glycoprotein Ib alpha polypeptide antibody Platelet membrane glycoprotein 1b alpha subunit antibody VWDP antibody
Abbreviation
GP1BA
Swiss Prot
P07359 Human
Cellular Locus
Membrane.
Host
Mouse
Species Reactivity
Human
Immunogen
Recombinant protein within human CD42b aa 100-350 / 652.
Isotype
IgG1
Conjugation
Non-conjugated
Type
Mouse monoclonal Antibody
Applications
IHC-P, FC
Positive Control
Human spleen tissue, human bone marrow tissue, Jurkat.
Concentration
2 mg/mL
Dilution
IHC-P: 1:1,000 ;FC: 1:50-1:100
Purity
Protein A affinity purified.
Form
Liquid
Buffer
1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 72 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
No

Frequently Asked Questions

What is the catalog number for CD42b Mouse Monoclonal Antibody [13G2]?

The catalog number for CD42b Mouse Monoclonal Antibody [13G2] is EM1902-15.

What sizes are available for CD42b Mouse Monoclonal Antibody [13G2]?

CD42b Mouse Monoclonal Antibody [13G2] is available in the following size(s): 100 µL.

Is CD42b Mouse Monoclonal Antibody [13G2] in stock?

CD42b Mouse Monoclonal Antibody [13G2] is currently made to order / not held in immediate stock. Contact us for lead time.

What is CD42b Mouse Monoclonal Antibody [13G2] used for?

Glycoprotein Ib (GP Ib) is a platelet surface membrane glycoprotein composed of a heterodimer, an alpha chain and a beta chain, that is linked by disulfide bonds. The Gp Ib functions as a receptor for von Willebrand factor (VWF). The complete receptor complex includes noncovalent association of the

What is the recommended incubation time for this antibody?

A suggested incubation time is provided in the recommended protocol on the datasheet, but may need adjusting depending on your sample type and detection system.

What should I check when this product first arrives?

Inspect the package immediately for transportation damage, ice loss, leakage, or breakage. Report any issues right away with photos and your order reference; our specialists will determine whether the product is still usable or needs replacing.

Does this cell line or biologic require a Material Transfer Agreement (MTA)?

Some products, including certain cell lines, plasmids, and tissue cultures, are subject to intellectual property terms and may require an MTA before we can ship. We’ll inform you in advance if this product requires one, and additional handling fees may apply.

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