MUC1 Mouse Monoclonal Antibody [A4D9]

About this product

This gene encodes a membrane-bound protein that is a member of the mucin family. Mucins are O-glycosylated proteins that play an essential role in forming protective mucous barriers on epithelial surfaces. These proteins also play a role in intracellular signaling. This protein is expressed on the apical surface of epithelial cells that line the mucosal surfaces of many different tissues including lung, breast stomach and pancreas. This protein is proteolytically cleaved into alpha and beta subunits that form a heterodimeric complex. The N-terminal alpha subunit functions in cell-adhesion and the C-terminal beta subunit is involved in cell signaling. Overexpression, aberrant intracellular localization, and changes in glycosylation of this protein have been associated with carcinomas. This gene is known to contain a highly polymorphic variable number tandem repeats (VNTR) domain. Alternate splicing results in multiple transcript variants.

Specifications

Catalog number

EM1902-32

Size / count

100 µL

Dry ice

No

Hazardous

No

Discontinued

No

CAS Number

9007-83-4

Product Name Alternative

ADMCKD antibody ADMCKD1 antibody Breast carcinoma associated antigen DF3 antibody Breast carcinoma-associated antigen DF3 antibody CA 15-3 antibody CA15 3 antibody CA15 3 antigen antibody CA15-3 antibody CA15.3 antibody Cancer antigen 15-3 antibody Carcinoma associated mucin antibody Carcinoma-associated mucin antibody CD 227 antibody CD227 antibody DF3 antigen antibody EMA antibody Episialin antibody Epithelial Membrane Antigen antibody H23 antigen antibody H23AG antibody KL 6 antibody KL-6 antibody KL6 antibody Krebs von den Lungen-6 antibody MAM 6 antibody MAM6 antibody MCD antibody MCKD antibody MCKD1 antibody Medullary cystic kidney disease 1 (autosomal dominant) antibody Medullary cystic kidney disease, autosomal dominant antibody MUC 1 antibody MUC-1 antibody MUC-1/SEC antibody MUC-1/X antibody MUC1 antibody MUC1-alpha antibody MUC1-beta antibody MUC1-CT antibody MUC1-NT antibody MUC1/ZD antibody MUC1_HUMAN antibody Mucin 1 antibody Mucin 1 cell surface associated antibody Mucin 1 transmembrane antibody Mucin 1, cell surface associated antibody Mucin-1 subunit beta antibody Peanut reactive urinary mucin antibody Peanut-reactive urinary mucin antibody PEM antibody PEMT antibody Polymorphic epithelial mucin antibody PUM antibody Tumor associated epithelial membrane antigen antibody Tumor associated epithelial mucin antibody Tumor associated mucin antibody Tumor-associated epithelial membrane antigen antibody Tumor-associated mucin antibody

Abbreviation

MUC1

Swiss Prot

P15941 Human

Cellular Locus

Apical cell membrane. Secreted. Nucleus, Cell membrane, Cytoplasm.

Host

Mouse

Species Reactivity

Human

Immunogen

Synthetic peptide of core peptide domain of human MUC1.

Isotype

IgG1

Conjugation

Non-conjugated

Type

Mouse monoclonal Antibody

Applications

IHC-P, FC, IF-Cell

Positive Control

Human breast tissue, human kidney tissue, human uterus tissue, human colon carcinoma tissue, human breast carcinoma tissue, MCF-7, HeLa.

Concentration

2 mg/mL

Dilution

IHC-P: 1:50-1:500 ;FC: 1:50-1:100 ;IF-Cell: 1:500

Purity

Protein G affinity purified.

Form

Liquid

Buffer

1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.

Molecular Weight

Predicted band size 122 kDa.

Storage Conditions

Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.

Recombinant Antibody

No