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Product details

GATA3 Mouse Monoclonal Antibody [A3G3]

Catalog number EM1902-33

Price for EM1902-33

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Size / count 100 µL

About this product

GATA3 is a transcription factor that in humans is encoded by the GATA3 gene. Studies in animal models and humans indicate that it controls the expression of a wide range of biologically and clinically important genes. The GATA3 transcription factor is critical for the embryonic development of various tissues as well as for inflammatory and humoral immune responses and the proper functioning of the endothelium of blood vessels. GATA3 haploinsufficiency (i.e. lose of one or the two inherited GATA3 genes) results in a congenital disorder termed the Barakat syndrome. Current clinical and laboratory research is focusing on determining the benefits of directly or indirectly blocking the action of GATA3 in inflammatory and allergic diseases such as asthma. It is also proposed to be a clinically important marker for various types of cancer, particularly those of the breast. However, the role, if any, of GATA3 in the development of these cancers is under study and remains unclear.

Specifications

Catalog number
EM1902-33
Size / count
100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Product Name Alternative
GATA 3 antibody GATA binding factor 3 antibody GATA binding protein 3 antibody GATA-binding factor 3 antibody Gata3 antibody GATA3_HUMAN antibody HDR antibody HDRS antibody MGC2346 antibody MGC5199 antibody MGC5445 antibody Trans acting T cell specific transcription factor GATA 3 antibody Trans-acting T-cell-specific transcription factor GATA-3 antibody
Abbreviation
Trans-acting T-cell-specific transcription factor GATA-3,GATA-binding factor 3
Swiss Prot
P23771 Human
Cellular Locus
Nucleus.
Host
Mouse
Species Reactivity
Human
Immunogen
Synthetic peptide within N-terminal Human GATA3.
Isotype
IgG2c
Conjugation
Non-conjugated
Type
Mouse monoclonal Antibody
Applications
WB, IF-Cell, IHC-P
Positive Control
SH-SY5Y cell lysate, MCF7 cell lysate, Jurkat cell lysate, SH-SY5Y, MCF-7, human breast carcinoma tissue.
Concentration
2 mg/mL
Dilution
WB: 1:500-1:2,000 ;IF-Cell: 1:50-1:200 ;IHC-P: 1:1,000
Purity
Protein A affinity purified.
Form
Liquid
Buffer
1*TBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 48 kDa.
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
No

Frequently Asked Questions

What is the catalog number for GATA3 Mouse Monoclonal Antibody [A3G3]?

The catalog number for GATA3 Mouse Monoclonal Antibody [A3G3] is EM1902-33.

What sizes are available for GATA3 Mouse Monoclonal Antibody [A3G3]?

GATA3 Mouse Monoclonal Antibody [A3G3] is available in the following size(s): 100 µL.

Is GATA3 Mouse Monoclonal Antibody [A3G3] in stock?

GATA3 Mouse Monoclonal Antibody [A3G3] is currently made to order / not held in immediate stock. Contact us for lead time.

What is GATA3 Mouse Monoclonal Antibody [A3G3] used for?

GATA3 is a transcription factor that in humans is encoded by the GATA3 gene. Studies in animal models and humans indicate that it controls the expression of a wide range of biologically and clinically important genes. The GATA3 transcription factor is critical for the embryonic development of variou

Do you ship this product with dry ice?

Some products, including certain cell lines and biologics, require dry ice for transportation, which carries an additional fee shown clearly in your quotation. Dry ice delivery isn’t always possible to every destination due to transit time or local restrictions, so we check feasibility in advance and you must store the goods at the correct temperature the moment they arrive.

Is this product species cross-reactive?

Cross-reactivity data, based on available testing, is listed under the reactivity section of the datasheet. Contact us if you need reactivity confirmed for a species not listed.

Is there an additional fee for hazardous or dry ice shipping of this product?

Yes, if this product requires dry ice or is classed as hazardous for transport, the additional fee will be explicitly shown in your quotation before you confirm the order, so there are no surprise charges later.

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