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Product details

CD166 Mouse Monoclonal Antibody [5-5]

Catalog number EM1902-36

Price for EM1902-36

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Size / count 100 µL

About this product

Cell adhesion molecule that mediates both heterotypic cell-cell contacts via its interaction with CD6, as well as homotypic cell-cell contacts . Promotes T-cell activation and proliferation via its interactions with CD6 . Contributes to the formation and maturation of the immunological synapse via its interactions with CD6 . Mediates homotypic interactions with cells that express ALCAM . Required for normal hematopoietic stem cell engraftment in the bone marrow . Mediates attachment of dendritic cells onto endothelial cells via homotypic interaction . Inhibits endothelial cell migration and promotes endothelial tube formation via homotypic interactions . Required for normal organization of the lymph vessel network. Required for normal hematopoietic stem cell engraftment in the bone marrow. Plays a role in hematopoiesis; required for normal numbers of hematopoietic stem cells in bone marrow. Promotes in vitro osteoblast proliferation and differentiation (By similarity). Promotes neurite extension, axon growth and axon guidance; axons grow preferentially on surfaces that contain ALCAM. Mediates outgrowth and pathfinding for retinal ganglion cell axons (By similarity).

Specifications

Catalog number
EM1902-36
Size / count
100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Product Name Alternative
Activated leukocyte cell adhesion molecule antibody ALCAM antibody ALCAM protein antibody CD 166 antibody CD166 antibody CD166 antigen antibody CD166_HUMAN antibody FLJ3851 antibody FLJ38514 antibody MEMD antibody MGC71733 antibody
Abbreviation
CD166 antigen,CD166,Activated leukocyte cell adhesion molecule,ALCAM
Swiss Prot
Q13740 Human
Cellular Locus
Cell membrane, Cell projection, Membrane, Secreted
Host
Mouse
Species Reactivity
Human
Immunogen
Recombinant protein within human CD166 aa 1-300.
Isotype
IgG1
Conjugation
Non-conjugated
Type
Mouse monoclonal Antibody
Applications
WB, IHC-P, IF-Cell, FC
Positive Control
PC-3M cell lysate, A549 cell lysate, SHSY5Y cell lysate, A431cells, Huvec celles, human liver tissue, THP-1 cells.
Concentration
2 mg/mL
Dilution
WB: 1:500-1:1,000 ;IHC-P: 1:50-1:200 ;IF-Cell: 1:50-1:100 ;FC: 1:50-1:100
Purity
Protein A affinity purified.
Form
Liquid
Buffer
1*TBS (pH7.4), 1%BSA, 50%Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 65 kDa.
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
No

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