Glutamine Synthetase Mouse Monoclonal Antibody [A3G2]

About this product

The protein encoded by this gene belongs to the glutamine synthetase family. It catalyzes the synthesis of glutamine from glutamate and ammonia in an ATP-dependent reaction. This protein plays a role in ammonia and glutamate detoxification, acid-base homeostasis, cell signaling, and cell proliferation. Glutamine is an abundant amino acid, and is important to the biosynthesis of several amino acids, pyrimidines, and purines. Mutations in this gene are associated with congenital glutamine deficiency, and overexpression of this gene was observed in some primary liver cancer samples. There are six pseudogenes of this gene found on chromosomes 2, 5, 9, 11, and 12. Alternative splicing results in multiple transcript variants.

Specifications

Catalog number

EM1902-39

Size / count

100 µL

Dry ice

No

Hazardous

No

Discontinued

No

CAS Number

9007-83-4

Product Name Alternative

cell proliferation-inducing protein 59 antibody Cgl2214 antibody GLNA antibody GLNA_HUMAN antibody GLNS antibody GLUL antibody Glutamate ammonia ligase antibody Glutamate decarboxylase antibody Glutamate--ammonia ligase antibody glutamine synthase antibody Glutamine synthetase antibody glutamine synthetase I antibody GS antibody PIG 43 antibody PIG 59 antibody PIG43 antibody PIG59 antibody Proliferation inducing protein 43 antibody

Abbreviation

GLUL

Swiss Prot

P15104 Human, P15105 Mouse, P09606 Rat

Cellular Locus

Microsome, Cytosol, Mitochondrion, Cell membrane.

Host

Mouse

Species Reactivity

Human, Mouse, Rat

Immunogen

Recombinant protein within human Glutamine synthetase aa 190-373.

Isotype

IgG2a

Conjugation

Non-conjugated

Type

Mouse monoclonal Antibody

Applications

WB, IHC-P, FC, mIHC, IF-Tissue

Positive Control

HeLa cell lysate, MCF7 cell lysate, HepG2 cell lysate, K-562 cell lysate, Jurkat cell lysate, HEK-293 cell lysate, SK-Br-3 cell lysate, human liver tissue lysate, human spleen tissue, mouse liver tissue, rat liver tissue, THP-1.

Concentration

2 mg/mL

Dilution

WB: 1:500-1:2,000 ;IHC-P: 1:500-1:2,000 ;FC: 1:50-1:100 ;mIHC: 1:2,000 ;IF-Tissue: 1:200-1:500

Purity

Protein G affinity purified.

Form

Liquid

Buffer

1*TBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.

Molecular Weight

Predicted band size: 42 kDa

Storage Conditions

Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.

Recombinant Antibody

No