IDH1 Mouse Monoclonal Antibody [A11-B4] — image 1 of 3

Product details

IDH1 Mouse Monoclonal Antibody [A11-B4]

Catalog number EM40705

Price for EM40705

Size / count 100 µL

About this product

Isocitrate dehydrogenase (IDH) is an enzyme that catalyzes the oxidative decarboxylation of isocitrate, producing alpha-ketoglutarate (α-ketoglutarate) and CO2. In humans, IDH exists in three isoforms: IDH3 catalyzes the third step of the citric acid cycle while converting NAD+ to NADH in the mitochondria. The isoforms IDH1 and IDH2 catalyze the same reaction outside the context of the citric acid cycle and use NADP+ as a cofactor instead of NAD+. They localize to the cytosol as well as the mitochondrion and peroxisome. Mutations in IDH1 are also implicated in cancer. Originally mutations in IDH1 were detected in an integrated genomic analysis of human glioblastoma multiforme. In addition to being mutated in diffuse gliomas, IDH1 has also been shown to harbor mutations in human acute myeloid leukemia (AML).

Specifications

Catalog number: EM40705
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Product Name Alternative: Cytosolic NADP isocitrate dehydrogenase antibody Cytosolic NADP-isocitrate dehydrogenase antibody Epididymis luminal protein 216 antibody Epididymis secretory protein Li 26 antibody HEL-216 antibody HEL-S-26 antibody ICDH antibody IDCD antibody IDH antibody IDH1 antibody IDHC_HUMAN antibody IDP antibody IDPC antibody Isocitrate dehydrogenase [NADP] cytoplasmic antibody Isocitrate dehydrogenase 1 (NADP+) soluble antibody NADP dependent isocitrate dehydrogenase cytosolic antibody NADP dependent isocitrate dehydrogenase peroxisomal antibody NADP (+)-specific ICDH antibody Oxalosuccinate decarboxylase antibody PICD antibody
Abbreviation: IDH1, PICD
Swiss Prot: O75874 Human, O88844 Mouse, P41562 Rat
Cellular Locus: Cytoplasm.
Host: Mouse
Species Reactivity: Human, Mouse, Rat, Monkey, Zebrafish
Immunogen: Synthetic peptide within Human IDH1 aa 101-150 / 414.
Isotype: IgG1
Conjugation: Non-conjugated
Type: Mouse monoclonal Antibody
Applications: WB, IHC-P
Positive Control: HepG2 cell lysate, HeLa cell lysate, HEK-293 cell lysate, A431 cell lysate, Neuro-2a cell lysate, PC-12 cell lysate, COS-1 cell lysate, human colon carcinoma tissue, human breast tissue, human kidney tissue.
Concentration: 2 mg/mL
Dilution: WB: 1:2,000 ;IHC-P: 1:100-1:200
Purity: Protein A affinity purified.
Form: Liquid
Buffer: 1*PBS (pH7.4), 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight: Predicted band size: 47 kDa
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody: No

Frequently Asked Questions

What is the catalog number for IDH1 Mouse Monoclonal Antibody [A11-B4]?

The catalog number for IDH1 Mouse Monoclonal Antibody [A11-B4] is EM40705.

What sizes are available for IDH1 Mouse Monoclonal Antibody [A11-B4]?

IDH1 Mouse Monoclonal Antibody [A11-B4] is available in the following size(s): 100 µL.

Is IDH1 Mouse Monoclonal Antibody [A11-B4] in stock?

IDH1 Mouse Monoclonal Antibody [A11-B4] is currently made to order / not held in immediate stock. Contact us for lead time.

What is IDH1 Mouse Monoclonal Antibody [A11-B4] used for?

What is the molecular weight of the target protein?

Molecular weight information, where applicable, is listed on the datasheet under target details, useful for confirming the correct band on western blot.

How long will it take to receive this product if it’s custom made?

Lead times depend on the product type: custom polyclonal antibodies typically take 12-14 weeks, monoclonal antibodies 15-17 weeks, made-to-order recombinant proteins 4-8 weeks, and made-to-order recombinant antibodies 6-8 weeks. These are estimates and may shift due to production delays.

What is the recommended dilution for this antibody?

A recommended dilution range for each validated application is provided on the datasheet, but optimal dilution should be titrated for your specific experimental system, sample type, and detection method.