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![FGFR2/CD332 Recombinant Mouse Monoclonal Antibody [A5-E10-G7-R] — image 1 of 3](https://cdn.genprice.uk/products/992/68dd1c8e061270361ea8250b/imageurl/em50103.webp)
Product details
Catalog number EM50103
Price for EM50103
Size / count 100 µL
Fibroblast growth factor receptor 2 (FGFR2) also known as CD332 has two naturally occurring isoforms FGFR2IIIb and FGFR2IIIc, created by splicing of the third immunoglobulin-like domain. FGFR2IIIb is predominantly found in ectoderm derived tissues and endothelial organ lining, i.e. skin and internal organs. FGFR2 has important roles in embryonic development and tissue repair, especially bone and blood vessels. Like the other members of the Fibroblast growth factor receptor family, these receptors signal by binding to their ligand and dimerisation (pairing of receptors), which causes the tyrosine kinase domains to initiate a cascade of intracellular signals. As mentioned, FGFR2 mutations are associated with craniosynostosis syndromes, which are skull malformations caused by premature fusion of cranial sutures and other disease features according to the mutation itself.
The catalog number for FGFR2/CD332 Recombinant Mouse Monoclonal Antibody [A5-E10-G7-R] is EM50103.
FGFR2/CD332 Recombinant Mouse Monoclonal Antibody [A5-E10-G7-R] is available in the following size(s): 100 µL.
FGFR2/CD332 Recombinant Mouse Monoclonal Antibody [A5-E10-G7-R] is currently made to order / not held in immediate stock. Contact us for lead time.
Fibroblast growth factor receptor 2 (FGFR2) also known as CD332 has two naturally occurring isoforms FGFR2IIIb and FGFR2IIIc, created by splicing of the third immunoglobulin-like domain. FGFR2IIIb is predominantly found in ectoderm derived tissues and endothelial organ lining, i.e. skin and internal
Immunogen or antigen details used to raise this antibody are listed on the product datasheet under immunogen information.
A recommended positive control, where one is specified by the manufacturer, is listed on the datasheet or in the assay protocol.
Storage conditions depend on the specific reagent and are listed on the product datasheet, with most antibodies and proteins requiring -20°C unless stated otherwise. It is your responsibility to store the product correctly immediately upon receipt; damage from improper storage after delivery is not eligible for replacement.
