Ku70 Mouse Monoclonal Antibody [D1-A6] — image 1 of 3

Product details

Ku70 Mouse Monoclonal Antibody [D1-A6]

Catalog number EM50109

Price for EM50109

Size / count 100 µL

About this product

Together, Ku70 and Ku80 make up the Ku heterodimer, which binds to DNA double-strand break ends and is required for the non-homologous end joining (NHEJ) pathway of DNA repair. It is also required for V (D)J recombination, which utilizes the NHEJ pathway to promote antigen diversity in the mammalian immune system.In addition to its role in NHEJ, Ku is also required for telomere length maintenance and subtelomeric gene silencing. Ku was originally identified when patients with systemic lupus erythematosus were found to have high levels of autoantibodies to the protein.

Specifications

Catalog number: EM50109
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Product Name Alternative: 5'-deoxyribose-5-phosphate lyase Ku70 antibody 5'-dRP lyase Ku70 antibody 70 kDa subunit of Ku antigen antibody ATP dependent DNA helicase 2 subunit 1 antibody ATP dependent DNA helicase II 70 kDa subunit antibody ATP-dependent DNA helicase 2 subunit 1 antibody ATP-dependent DNA helicase II 70 kDa subunit antibody CTC box binding factor 75 kDa subunit antibody CTC box-binding factor 75 kDa subunit antibody CTC75 antibody CTCBF antibody DNA repair protein XRCC6 antibody G22P1 antibody Ku 70 antibody Ku autoantigen p70 subunit antibody Ku autoantigen, 70kDa antibody Ku p70 antibody Ku70 antibody Ku70 DNA binding component of DNA-dependent proteinkinase complex (thyroid autoantigen 70 kDa antibody Kup70 antibody Lupus Ku autoantigen protein p70 antibody ML8 antibody Thyroid autoantigen 70kD (Ku antigen) antibody Thyroid autoantigen antibody Thyroid lupus autoantigen antibody Thyroid lupus autoantigen p70 antibody Thyroid-lupus autoantigen antibody TLAA antibody X ray repair complementing defective repair in Chinese hamster cells 6 antibody X-ray repair complementing defective repair in Chinese hamster cells 6 antibody X-ray repair cross-complementing protein 6 antibody XRCC 6 antibody Xrcc6 antibody XRCC6_HUMAN antibody
Abbreviation: 5'-dRP lyase Ku70,CTC75,CTCBF,Ku70,TLAA
Swiss Prot: P12956 Human, P23475 mouse
Cellular Locus: Nucleus.
Host: Mouse
Species Reactivity: Human, Mouse
Immunogen: Recombinant protein within human Ku70 aa 1-150/609.
Isotype: IgG2a
Conjugation: Non-conjugated
Type: Mouse monoclonal Antibody
Applications: WB, IHC-P
Positive Control: Hela cell lysates, HepG2 cell lysates, A431 cell lysates, D3 cell lysates, 293T cell lysates, A549 cell lysates, COS-1 cell lysates, human kidney tissue lysates, human liver tissue lysates, human brain tissue lysates, human thymus tissue lysates, human placentae tissue lysates, mouse kidney tissue lysates, mouse liver tissue lysates, mouse thymus tissue lysates, mouse testis tissue lysates, human tonsil tissue,human breast cancer tissue.
Concentration: 2 mg/mL
Dilution: WB: 1:2,000 ;IHC-P: 1:100-1:200
Purity: Protein A affinity purified.
Form: Liquid
Buffer: 1*PBS (pH7.4), 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight: Predicted band size: 70 kDa
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody: No

Frequently Asked Questions

What is the catalog number for Ku70 Mouse Monoclonal Antibody [D1-A6]?

The catalog number for Ku70 Mouse Monoclonal Antibody [D1-A6] is EM50109.

What sizes are available for Ku70 Mouse Monoclonal Antibody [D1-A6]?

Ku70 Mouse Monoclonal Antibody [D1-A6] is available in the following size(s): 100 µL.

Is Ku70 Mouse Monoclonal Antibody [D1-A6] in stock?

Ku70 Mouse Monoclonal Antibody [D1-A6] is currently made to order / not held in immediate stock. Contact us for lead time.

What is Ku70 Mouse Monoclonal Antibody [D1-A6] used for?

What should I check when this product first arrives?

Inspect the package immediately for transportation damage, ice loss, leakage, or breakage. Report any issues right away with photos and your order reference; our specialists will determine whether the product is still usable or needs replacing.

Does this cell line or biologic require a Material Transfer Agreement (MTA)?

Some products, including certain cell lines, plasmids, and tissue cultures, are subject to intellectual property terms and may require an MTA before we can ship. We’ll inform you in advance if this product requires one, and additional handling fees may apply.

What should I do if I need to report a performance issue with a specific lot of this product?

Provide the catalogue number, product name, lot number, and your experimental results to our technical support team. They’ll investigate and, if needed, escalate to the manufacturer, provided the product was used before expiry and stored correctly.