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Product details

BAX Rabbit Polyclonal Antibody

Catalog number ER0907

Price for ER0907

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Size / count 100 µL

About this product

BAX is a member of the Bcl-2 gene family. Apoptosis regulator BAX promotes apoptosis by binding to and antagonizing the Bcl-2 protein. In healthy mammalian cells, the majority of BAX is found in the cytosol, but upon initiation of apoptotic signaling, Bax undergoes a conformational shift. Upon induction of apoptosis, BAX becomes organelle membrane-associated, and in particular, mitochondrial membrane associated. The expression of BAX is upregulated by the tumor suppressor protein p53, and BAX has been shown to be involved in p53-mediated apoptosis. The p53 protein is a transcription factor that, when activated as part of the cell's response to stress, regulates many downstream target genes, including BAX.

Specifications

Catalog number
ER0907
Size / count
100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Product Name Alternative
Apoptosis regulator BAX antibody BAX antibody Bax-protein antibody BAX_HUMAN antibody BAXA antibody Baxdelta2G9 antibody Baxdelta2G9omega antibody Baxdelta2omega antibody Bcl-2-like protein 4 antibody BCL2 associated X protein antibody BCL2 associated X protein omega antibody BCL2 associated X protein transcript variant delta2 antibody Bcl2-L-4 antibody BCL2L4 antibody membrane isoform alpha antibody
Abbreviation
Bcl2-L-4
Swiss Prot
Q07812 Human, Q07813 Mouse, Q63690 Rat
Cellular Locus
Mitochondrion membrane, cytoplasm.
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Immunogen
Synthetic peptide within Human BAX aa 1-50 / 192.
Isotype
IgG
Conjugation
Non-conjugated
Type
Rabbit polyclonal Antibody
Applications
WB, IF-Cell, IHC-P
Positive Control
HeLa cell lysate, MCF7 cell lysate, HEK-293 cell lysate, Daudi cell lysate, Raji cell lysate, Jurkat cell lysate, HepG2, F9, SHSY5Y, human colon carcinoma tissue, mouse kidney tissue.
Concentration
1 mg/mL
Dilution
WB: 1:5,000-1:20,000 ;IF-Cell: 1:200 ;IHC-P: 1:1,000
Purity
Immunogen affinity purified.
Form
Liquid
Buffer
1*PBS (pH7.4), 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 21 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody
No

Frequently Asked Questions

What is the catalog number for BAX Rabbit Polyclonal Antibody?

The catalog number for BAX Rabbit Polyclonal Antibody is ER0907.

What sizes are available for BAX Rabbit Polyclonal Antibody?

BAX Rabbit Polyclonal Antibody is available in the following size(s): 100 µL.

Is BAX Rabbit Polyclonal Antibody in stock?

BAX Rabbit Polyclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

What is BAX Rabbit Polyclonal Antibody used for?

BAX is a member of the Bcl-2 gene family. Apoptosis regulator BAX promotes apoptosis by binding to and antagonizing the Bcl-2 protein. In healthy mammalian cells, the majority of BAX is found in the cytosol, but upon initiation of apoptotic signaling, Bax undergoes a conformational shift. Upon induc

Do you offer bulk or custom quantities of this product?

Yes. Ordering two or more units, or combining this with other products, usually qualifies for a discount depending on quantity. Contact our sales team with your required volume for a custom quote.

Do you provide a Certificate of Analysis (CoA) for this product?

A Certificate of Analysis is available for most products upon request. Contact our support team with the lot number to obtain the relevant CoA.

Is this product suitable for live cell imaging?

Suitability for live cell imaging depends on the specific reagent and conjugate used. Check the datasheet for imaging-specific validation, or contact us for guidance.

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