SIRT1 Rabbit Polyclonal Antibody — image 1 of 3

Product details

SIRT1 Rabbit Polyclonal Antibody

Catalog number ER130811

Price for ER130811

Size / count 100 µL

About this product

SirT1, the mammalian ortholog of Sir2, is a nuclear protein implicated in the regulation of many cellular processes, including apoptosis, cellular senescence, endocrine signaling, glucose homeostasis, aging, and longevity. Targets of SirT1 include acetylated p53, p300, Ku70, forkhead (FoxO) transcription factors, PPARγ, and the PPARγ coactivator-1α (PGC-1α) protein. Deacetylation of p53 and FoxO transcription factors represses apoptosis and increases cell survival. SirT1 deacetylase activity is inhibited by nicotinamide and activated by resveratrol.

Specifications

Catalog number: ER130811
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Product Name Alternative: 75SirT1 antibody hSIR2 antibody hSIRT1 antibody HST2, S. cerevisiae, homolog of antibody NAD dependent deacetylase sirtuin 1 antibody NAD dependent protein deacetylase sirtuin 1 antibody OTTHUMP00000198111 antibody OTTHUMP00000198112 antibody Regulatory protein SIR2 homolog 1 antibody SIR1_HUMAN antibody SIR2 antibody SIR2 like 1 antibody SIR2 like protein 1 antibody SIR2, S.cerevisiae, homolog-like 1 antibody SIR2-like protein 1 antibody SIR2ALPHA antibody SIR2L1 antibody Sirt1 antibody SirtT1 75 kDa fragment antibody Sirtuin (silent mating type information regulation 2 homolog) 1 (S. cerevisiae) antibody Sirtuin 1 antibody Sirtuin type 1 antibody
Abbreviation: hSIRT1,hSIR2
Swiss Prot: Q96EB6 Human
Cellular Locus: Nucleus, cytoplasm, Mitochondrion.
Host: Rabbit
Species Reactivity: Human, Mouse
Immunogen: Synthetic peptide within Human SIRT1 aa 698-747 / 747.
Isotype: IgG
Conjugation: Non-conjugated
Type: Rabbit polyclonal Antibody
Applications: WB, IHC-P, FC, IF-Cell
Positive Control: Hela cell lysate, Jurkat cell lysate, F9 cell lysate, HeLa, F9, human colon carcinoma tissue, human lung carcinoma tissue, mouse liver tissue, mouse testis tissue.
Concentration: 1 mg/mL
Dilution: WB: 1:1,000-1:2,000 ;IHC-P: 1:200 ;FC: 1:1,000 ;IF-Cell: 1:100
Purity: Immunogen affinity purified.
Form: Liquid
Buffer: 1*PBS (pH7.4), 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight: Predicted band size: 82 kDa
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody: No

Frequently Asked Questions

What is the catalog number for SIRT1 Rabbit Polyclonal Antibody?

The catalog number for SIRT1 Rabbit Polyclonal Antibody is ER130811.

What sizes are available for SIRT1 Rabbit Polyclonal Antibody?

SIRT1 Rabbit Polyclonal Antibody is available in the following size(s): 100 µL.

Is SIRT1 Rabbit Polyclonal Antibody in stock?

SIRT1 Rabbit Polyclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

What is SIRT1 Rabbit Polyclonal Antibody used for?

Do you ship this product with dry ice?

Some products, including certain cell lines and biologics, require dry ice for transportation, which carries an additional fee shown clearly in your quotation. Dry ice delivery isn’t always possible to every destination due to transit time or local restrictions, so we check feasibility in advance and you must store the goods at the correct temperature the moment they arrive.

Is this product species cross-reactive?

Cross-reactivity data, based on available testing, is listed under the reactivity section of the datasheet. Contact us if you need reactivity confirmed for a species not listed.

Is there an additional fee for hazardous or dry ice shipping of this product?

Yes, if this product requires dry ice or is classed as hazardous for transport, the additional fee will be explicitly shown in your quotation before you confirm the order, so there are no surprise charges later.