PHF10 Rabbit Polyclonal Antibody — image 1 of 3

Product details

PHF10 Rabbit Polyclonal Antibody

Catalog number ER1511-14

Price for ER1511-14

Size / count 100 µL

About this product

Involved in transcription activity regulation by chromatin remodeling. Belongs to the neural progenitors-specific chromatin remodeling complex (npBAF complex) and is required for the proliferation of neural progenitors. During neural development a switch from a stem/progenitor to a post-mitotic chromatin remodeling mechanism occurs as neurons exit the cell cycle and become committed to their adult state. The transition from proliferating neural stem/progenitor cells to post-mitotic neurons requires a switch in subunit composition of the npBAF and nBAF complexes. As neural progenitors exit mitosis and differentiate into neurons, npBAF complexes which contain ACTL6A/BAF53A and PHF10/BAF45A, are exchanged for homologous alternative ACTL6B/BAF53B and DPF1/BAF45B or DPF3/BAF45C subunits in neuron-specific complexes (nBAF). The npBAF complex is essential for the self-renewal/proliferative capacity of the multipotent neural stem cells. The nBAF complex along with CREST plays a role regulating the activity of genes essential for dendrite growth.

Specifications

Catalog number: ER1511-14
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Product Name Alternative: BAF45a antibody BRG1-associated factor 45a antibody FLJ10975 antibody MGC111009 antibody PHD finger protein 10 antibody PHD finger protein 10, isoform a antibody PHD zinc finger protein XAP135 antibody Phf10 antibody PHF10_HUMAN antibody XAP135 antibody
Abbreviation: BAF45a
Swiss Prot: Q8WUB8 Human, Q9D8M7 Mouse, Q4V7A6 Rat
Cellular Locus: Nucleus.
Host: Rabbit
Species Reactivity: Human, Mouse, Rat
Immunogen: Recombinant protein within Human PHF10 aa 172-374 / 498.
Isotype: IgG
Conjugation: Non-conjugated
Type: Rabbit polyclonal Antibody
Applications: WB, IHC-P
Positive Control: Hela, rat testis tissue, human tonsil tissue, human liver cancer tissue, human kidney tissue, mouse colon tissue.
Concentration: 1 mg/mL
Dilution: WB: 1:500-1:1,000 ;IHC-P: 1:50-1:200
Purity: Immunogen affinity purified.
Form: Liquid
Buffer: 1*PBS (pH7.4), 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight: Predicted band size: 56 kDa
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody: No

Frequently Asked Questions

What is the catalog number for PHF10 Rabbit Polyclonal Antibody?

The catalog number for PHF10 Rabbit Polyclonal Antibody is ER1511-14.

What sizes are available for PHF10 Rabbit Polyclonal Antibody?

PHF10 Rabbit Polyclonal Antibody is available in the following size(s): 100 µL.

Is PHF10 Rabbit Polyclonal Antibody in stock?

PHF10 Rabbit Polyclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

What is PHF10 Rabbit Polyclonal Antibody used for?

How do I reconstitute this lyophilized product?

Reconstitution instructions, including the recommended diluent and final concentration, are provided on the datasheet. Aliquot immediately after reconstitution to avoid repeated freeze-thaw cycles.

What is the recommended incubation time for this antibody?

A suggested incubation time is provided in the recommended protocol on the datasheet, but may need adjusting depending on your sample type and detection system.

What should I check when this product first arrives?

Inspect the package immediately for transportation damage, ice loss, leakage, or breakage. Report any issues right away with photos and your order reference; our specialists will determine whether the product is still usable or needs replacing.