NM23 Rabbit Polyclonal Antibody

About this product

Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. Possesses nucleoside-diphosphate kinase, serine/threonine-specific protein kinase, geranyl and farnesyl pyrophosphate kinase, histidine protein kinase and 3'-5' exonuclease activities. Involved in cell proliferation, differentiation and development, signal transduction, G protein-coupled receptor endocytosis, and gene expression. Required for neural development including neural patterning and cell fate determination. During GZMA-mediated cell death, works in concert with TREX1. NME1 nicks one strand of DNA and TREX1 removes bases from the free 3' end to enhance DNA damage and prevent DNA end reannealing and rapid repair.

Specifications

Catalog number

ER1603-4

Size / count

100 µL

Dry ice

No

Hazardous

No

Discontinued

No

CAS Number

9007-83-4

Product Name Alternative

AWD antibody AWD, drosophila, homolog of antibody GAAD antibody Granzyme A activated DNase antibody Granzyme A-activated DNase antibody GZMA activated DNase antibody Metastasis inhibition factor NM23 antibody NB antibody NBS antibody NDK A antibody NDKA antibody NDKA_HUMAN antibody NDP kinase A antibody NDPK-A antibody NDPKA antibody NM23 antibody NM23 long variant, included antibody nm23-H1 antibody NM23-M1 antibody NM23H1B, included antibody NME/NM23 nucleoside diphosphate kinase 1 antibody Nme1 antibody NME1-NME2 spliced read-through transcript, included antibody Non-metastatic cells 1, protein (NM23A) expressed in antibody Nonmetastatic cells 1, protein expressed in antibody Nonmetastatic protein 23 antibody Nonmetastatic protein 23, homolog 1 antibody Nucleoside diphosphate kinase A antibody Tumor metastatic process-associated protein antibody

Abbreviation

NDK A, NDP kinase A, GAAD, NME1, NDPKA, NM23

Swiss Prot

P15531 Human, P15532 Mouse

Cellular Locus

Cytoplasm. Nucleus.

Host

Rabbit

Species Reactivity

Human, Mouse

Immunogen

Synthetic peptide within human USP36 aa 64-128.

Isotype

IgG

Conjugation

Non-conjugated

Type

Rabbit polyclonal Antibody

Applications

IF-Cell, IHC-P, FC, WB

Positive Control

Hela, HepG2, MCF-7, human lung cancer tissue, human breast cancer tissue, mouse brain tissue.

Concentration

1 mg/mL

Dilution

IF-Cell: 1:50-1:200;IHC-P: 1:50-1:200;FC: 1:50-1:100;WB: 1:500

Purity

Immunogen affinity purified.

Form

Liquid

Buffer

1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.

Molecular Weight

17/19 kDa

Storage Conditions

Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Recombinant Antibody

No