CD71 Rabbit Polyclonal Antibody — image 1 of 3

Product details

CD71 Rabbit Polyclonal Antibody

Catalog number ER1706-35

Price for ER1706-35

Size / count 100 µL

About this product

CD71, also known as the transferrin receptor (TFR), is a type II membrane glycoprotein that exists as a disulfide-linked homodimer of two identical subunits. CD71 binds to two molecules of transferrin and a serum iron-transport protein, and directs the cellular uptake of iron via receptor-mediated endocytosis. CD71 is expressed, typically at high levels, on all proliferating cells, reticulocytes and erythroid precursors. It is not expressed on resting leukocytes, but is upregulated upon activation of lymphocytes, monocytes and macrophages. CD71 is also found on most dividing cells and on brain endothelium. A second transferrin receptor, TFR2, also mediates the uptake of transferrin-bound iron. TFR2 is a two-subunit homodimer and is highly expressed in liver as well as in hepatocytes and erythroid precursors. Mutations in the TFR2 gene result in hereditary hemochromatosis type III (HFE3), an iron overloading disorder predominant in Caucasians.

Specifications

Catalog number: ER1706-35
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Product Name Alternative: CD 71 antibody CD71 antibody CD71 antigen antibody IMD46 antibody OTTHUMP00000208523 antibody OTTHUMP00000208524 antibody OTTHUMP00000208525 antibody p90 antibody sTfR antibody T9 antibody TFR 1 antibody TfR antibody TfR1 antibody TFR1_HUMAN antibody TFRC antibody TR antibody Transferrin receptor (p90 CD71) antibody Transferrin receptor protein 1, serum form antibody Trfr antibody
Abbreviation: TR, TfR, TfR1, Trfr, sTfR, TFRC
Swiss Prot: P02786 Human
Cellular Locus: Secreted and Cell membrane. Melanosome.
Host: Rabbit
Species Reactivity: Human
Immunogen: Recombinant protein within Human CD71 aa 463-750 / 760.
Isotype: IgG
Conjugation: Non-conjugated
Type: Rabbit polyclonal Antibody
Applications: IHC-P
Positive Control: Human lung cancer tissue, human placenta tissue.
Concentration: 1 mg/mL
Dilution: IHC-P: 1:1,000
Purity: Protein A affinity purified.
Form: Liquid
Buffer: 1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight: Predicted band size: 85 kDa
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody: No

Frequently Asked Questions

What is the catalog number for CD71 Rabbit Polyclonal Antibody?

The catalog number for CD71 Rabbit Polyclonal Antibody is ER1706-35.

What sizes are available for CD71 Rabbit Polyclonal Antibody?

CD71 Rabbit Polyclonal Antibody is available in the following size(s): 100 µL.

Is CD71 Rabbit Polyclonal Antibody in stock?

CD71 Rabbit Polyclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

What is CD71 Rabbit Polyclonal Antibody used for?

What should I check when this product first arrives?

Inspect the package immediately for transportation damage, ice loss, leakage, or breakage. Report any issues right away with photos and your order reference; our specialists will determine whether the product is still usable or needs replacing.

Does this cell line or biologic require a Material Transfer Agreement (MTA)?

Some products, including certain cell lines, plasmids, and tissue cultures, are subject to intellectual property terms and may require an MTA before we can ship. We’ll inform you in advance if this product requires one, and additional handling fees may apply.

What should I do if I need to report a performance issue with a specific lot of this product?

Provide the catalogue number, product name, lot number, and your experimental results to our technical support team. They’ll investigate and, if needed, escalate to the manufacturer, provided the product was used before expiry and stored correctly.