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Product details

Cdc25C Rabbit Polyclonal Antibody

Catalog number ER1706-38

Price for ER1706-38

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Size / count 100 µL

About this product

Cell cycle events are regulated by the sequential activation and deactivation of cyclin-dependent kinases (Cdks), including Cdk2 and Cdc2. Cdk2 in complexes with cyclin E and cyclin A appears necessary for the onset and progression of DNA replication, while the Cdc2 kinase in complexes with cyclin A or cyclin B is required for the initiation of cell division. Wee 1 has been identified as a protein kinase that suppresses the entry into mitosis by mediating inhibiting tyrosine phosphorylation of Cdc2 p34. In contrast, members of the Cdc25 family of protein phosphatases function as mitotic activators by dephosphorylation of Cdc2 p34 on regulatory tyrosine and possibly threonine residues. The Cdc25 gene family consists of at least three members that share approximately 40% identity in their most conserved carboxy-terminal sequences.

Specifications

Catalog number
ER1706-38
Size / count
100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Product Name Alternative
CDC 25 antibody Cdc 25C antibody CDC25 antibody CDC25C antibody Cell division cycle 25 homolog C antibody Cell division cycle 25C antibody Cell division cycle 25C protein antibody Dual specificity phosphatase Cdc25C antibody M phase inducer phosphatase 3 antibody M-phase inducer phosphatase 3 antibody Mitosis inducer CDC25 antibody MPIP3 antibody MPIP3_HUMAN antibody Phosphotyrosine phosphatase antibody PPP1R60 antibody protein phosphatase 1, regulatory subunit 60 antibody
Abbreviation
CDC25C
Swiss Prot
P30307 Human, P48967 Mouse
Cellular Locus
Nucleus.
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Immunogen
Synthetic peptide within C-terminal human Cdc25C.
Isotype
IgG
Conjugation
Non-conjugated
Type
Rabbit polyclonal Antibody
Applications
WB, IF-Cell, IHC-P, FC
Positive Control
Human skin tissue lysate, A431, HUVEC, LOVO, rat brain tissue, human placenta tissue, mouse uterus tissue.
Concentration
1 mg/mL
Dilution
WB: 1:500-1:1,000;IF-Cell: 1:500-1:2,000;IHC-P: 1:50-1:200;FC: 1:50-1:100
Purity
Immunogen affinity purified.
Form
Liquid
Buffer
1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
53 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody
No

Frequently Asked Questions

What is the catalog number for Cdc25C Rabbit Polyclonal Antibody?

The catalog number for Cdc25C Rabbit Polyclonal Antibody is ER1706-38.

What sizes are available for Cdc25C Rabbit Polyclonal Antibody?

Cdc25C Rabbit Polyclonal Antibody is available in the following size(s): 100 µL.

Is Cdc25C Rabbit Polyclonal Antibody in stock?

Cdc25C Rabbit Polyclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

What is Cdc25C Rabbit Polyclonal Antibody used for?

Cell cycle events are regulated by the sequential activation and deactivation of cyclin-dependent kinases (Cdks), including Cdk2 and Cdc2. Cdk2 in complexes with cyclin E and cyclin A appears necessary for the onset and progression of DNA replication, while the Cdc2 kinase in complexes with cyclin A

Is this product tested for endotoxin levels?

Endotoxin testing status is noted on the datasheet where applicable, particularly for recombinant proteins intended for cell-based or functional assays. If this isn’t listed and you need confirmation, contact support with the catalogue number.

Can I request additional validation data, such as western blot images, for this product?

Additional data may be available on request. Contact our technical support team with the catalogue number and we’ll check what supporting documentation the supplier can provide.

What documentation should I request if this product is used for a regulated or intellectual-property-sensitive application?

If the product is subject to intellectual property protections, we’ll advise on any MTA or usage restrictions before shipping. Let us know your intended end use so we can confirm what’s required upfront.

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