HMGB2 Rabbit Polyclonal Antibody — image 1 of 3

Product details

HMGB2 Rabbit Polyclonal Antibody

Catalog number ER1706-52

Price for ER1706-52

Size / count 100 µL

About this product

High mobility group (HMG) proteins 1 and 2 are ubiquitous non-histone components of chromatin. Evidence suggests that the binding of HMG proteins to DNA induces alterations in the DNA architecture including DNA bending and unwinding of the helix. HMG proteins synergize with Oct-2, members of the NFκB family, ATF-2 and c-Jun to activate transcription. Other studies indicate that phosphorylation of HMG protein is required to stimulate the transcriptional activity of the protein. Human HMG-1 and HMG-2 both contain two DNA-binding domains, termed HMG boxes. HMG proteins bind single-stranded DNA but induce conformational changes in double-stranded DNA alone.

Specifications

Catalog number: ER1706-52
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Product Name Alternative: C80539 antibody High mobility group (nonhistone chromosomal) protein 2 antibody High mobility group box 2 antibody High mobility group protein 2 antibody High mobility group protein B2 antibody HMG 2 antibody HMG B2 antibody HMG-2 antibody HMG2 antibody HMGB2 antibody HMGB2_HUMAN antibody
Abbreviation: HMG-2, HMGB2, HMG2
Swiss Prot: P26583 Human, P30681 Mouse, P52925 Rat
Cellular Locus: Secreted. Nucleus. Cytoplasm.
Host: Rabbit
Species Reactivity: Human, Mouse, Rat
Immunogen: Recombinant protein within human HMGB2 aa 22-172.
Isotype: IgG
Conjugation: Non-conjugated
Type: Rabbit polyclonal Antibody
Applications: WB, IF-Cell, IHC-P
Positive Control: Mouse testis tissue, LOVO, SH-SY5Y, rat brain tissue, human tonsil tissue, human kidney tissue.
Concentration: 1 mg/mL
Dilution: WB: 1:500-1:1,000;IF-Cell: 1:50-1:200;IHC-P: 1:50-1:200
Purity: Immunogen affinity purified.
Form: Liquid
Buffer: 1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight: Predicted band size: 24 kDa
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody: No

Frequently Asked Questions

What is the catalog number for HMGB2 Rabbit Polyclonal Antibody?

The catalog number for HMGB2 Rabbit Polyclonal Antibody is ER1706-52.

What sizes are available for HMGB2 Rabbit Polyclonal Antibody?

HMGB2 Rabbit Polyclonal Antibody is available in the following size(s): 100 µL.

Is HMGB2 Rabbit Polyclonal Antibody in stock?

HMGB2 Rabbit Polyclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

What is HMGB2 Rabbit Polyclonal Antibody used for?

Do you provide a Certificate of Analysis (CoA) for this product?

A Certificate of Analysis is available for most products upon request. Contact our support team with the lot number to obtain the relevant CoA.

Is this product suitable for live cell imaging?

Suitability for live cell imaging depends on the specific reagent and conjugate used. Check the datasheet for imaging-specific validation, or contact us for guidance.

Is this product covered by a money-back guarantee?

Yes, we guarantee a full refund or store credit if this product arrives damaged beyond usability, or has a genuine performance issue under proper usage and storage, provided you report it immediately with evidence. Claims after the expiration date or due to improper storage after receipt are excluded.