AMACR Rabbit Polyclonal Antibody — image 1 of 3

Product details

AMACR Rabbit Polyclonal Antibody

Catalog number ER1706-60

Price for ER1706-60

Size / count 100 µL

About this product

P504S, also known as AMACR (α-methylacyl-CoA racemase), 2-methylacyl-CoA racemase or RACE, is an enzyme belonging to the caiB/baiF CoA-transferase family. Localizing to the peroxisome and mitochondrion, P504S plays a role in the metabolism of branched-chain fatty acids and bile acid intermediates. More specifically, P504S catalyzes the conversion of pristanoyl-CoA and C27-bile acyl-CoAs to their (S)-stereoisomers which can then be degraded by peroxisomal β-oxidation. Mutations in the gene encoding P504S can lead to AMACR deficiency, a disease characterized by increased concentrations of pristanic acid that is associated with adult onset sensory motor neuropathy, and/or CBAS4 (congenital bile acid synthesis defect type 4), a disorder characterized by intrahepatic cholestasis, absence of cholic acid from bile, neonatal jaundice and bile duct deficiency. In addition, P504S is overexpressed in prostate cancer and is believed to be functionally important for prostate cancer cell growth.

Specifications

Catalog number: ER1706-60
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Product Name Alternative: 2 arylpropionyl CoA epimerase antibody 2 methylacyl CoA racemase antibody 2-methylacyl-CoA racemase antibody Alpha methylacyl CoA racemase antibody Alpha methylacyl Coenzyme A racemase antibody Alpha methylacyl-CoA racemase deficiency, included antibody Alpha-methylacyl-CoA racemase antibody Amacr antibody AMACR deficiency, included antibody AMACR_HUMAN antibody CBAS4 antibody Da1-8 antibody EC 5.1.99.4 antibody Macr1 antibody Methylacyl CoA racemase alpha antibody RACE antibody RM antibody
Abbreviation: AMACR
Swiss Prot: Q9UHK6 Human, O09174 Mouse
Cellular Locus: Mitochondrion. Peroxisome.
Host: Rabbit
Species Reactivity: Human, Mouse
Immunogen: Recombinant protein within Human AMACR aa 1-382 / 382.
Isotype: IgG
Conjugation: Non-conjugated
Type: Rabbit polyclonal Antibody
Applications: WB, IF-Cell, IHC-P, FC
Positive Control: Human kidney tissue, mouse liver tissue lysate, Siha, SW480, HepG2, human liver tissue, human colon cancer tissue, mouse colon tissue, PC-3M.
Concentration: 1 mg/mL
Dilution: WB: 1:500;IF-Cell: 1:50-1:100;IHC-P: 1:50-1:1,000;FC: 1:50-1:100
Purity: Immunogen affinity purified.
Form: Liquid
Buffer: 1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight: Predicted band size: 42 kDa
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody: No

Frequently Asked Questions

What is the catalog number for AMACR Rabbit Polyclonal Antibody?

The catalog number for AMACR Rabbit Polyclonal Antibody is ER1706-60.

What sizes are available for AMACR Rabbit Polyclonal Antibody?

AMACR Rabbit Polyclonal Antibody is available in the following size(s): 100 µL.

Is AMACR Rabbit Polyclonal Antibody in stock?

AMACR Rabbit Polyclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

What is AMACR Rabbit Polyclonal Antibody used for?

What documentation should I request if this product is used for a regulated or intellectual-property-sensitive application?

If the product is subject to intellectual property protections, we’ll advise on any MTA or usage restrictions before shipping. Let us know your intended end use so we can confirm what’s required upfront.

Is this antibody conjugated?

Conjugation status, such as unconjugated, HRP, FITC, or biotin, is specified in the product name and confirmed on the datasheet.

What is the sensitivity of this ELISA kit?

Assay sensitivity, including the minimum detectable dose, is listed on the datasheet. Kits that are assembled on order typically ship within 2-4 weeks.