DLL4 Rabbit Polyclonal Antibody

About this product

The LIN-12/Notch family of transmembrane receptors is believed to play a central role in development by regulating cell fate decisions. Notch proteins have been found to be overexpressed or rearranged in human tumors. Ligands for Notch include Jagged, Jagged-2 and Delta. While blocking the differentiation of progenitor cells into the B-cell lineage, Delta promotes the emergence of a population of cells with T cell/NK-cell characteristics. The protein is a membrane protein expressed in heart, pancreas, brain and muscle during gastrulation and early organogenesis and in adult heart and lung. Delta-4 is a membrane protein that activates Notch-1 and Notch-4. It is expressed in a wide range of adult and fetal tissues, especially in vascular endothelium.

Specifications

Catalog number

ER1706-63

Size / count

100 µL

Dry ice

No

Hazardous

No

Discontinued

No

CAS Number

9007-83-4

Product Name Alternative

AOS6 antibody Delta 4 antibody delta 4 precursor antibody Delta ligand 4 antibody delta ligand 4 precursor antibody Delta like 4 antibody Delta like 4 homolog antibody Delta like 4 protein antibody Delta like canonical Notch ligand 4 antibody Delta like protein 4 antibody Delta-like 4 (Drosophila) antibody Delta-like protein 4 antibody Delta4 antibody DLL 4 antibody Dll4 antibody DLL4_HUMAN antibody Drosophila Delta homolog 4 antibody hdelta2 antibody Homeobox protein DLL-4 antibody MGC126344 antibody Notch ligand delta 2 antibody Notch ligand DLL4 antibody Notch ligand DLL4 precursor antibody XDLL-4 antibody

Abbreviation

Delta4, DLL4, UNQ1895/PRO4341

Swiss Prot

Q9NR61 Human, D3ZHH1 Rat

Cellular Locus

Cell membrane.

Host

Rabbit

Species Reactivity

Human, Rat

Immunogen

Synthetic peptide within human DLL4 aa 121-159.

Isotype

IgG

Conjugation

Non-conjugated

Type

Rabbit polyclonal Antibody

Applications

WB, IF-Cell, IHC-P, FC

Positive Control

Human lung tissue lysate, 293T, HUVEC, PMVEC, human kidney tissue.

Concentration

1 mg/mL

Dilution

WB: 1:500-1:1,000;IF-Cell: 1:50-1:200;IHC-P: 1:50-1:200;FC: 1:50-1:100

Purity

Immunogen affinity purified.

Form

Liquid

Buffer

1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.

Molecular Weight

Predicted band size: 75 kDa

Storage Conditions

Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Recombinant Antibody

No