Cullin-3 Rabbit Polyclonal Antibody — image 1 of 3

Product details

Cullin-3 Rabbit Polyclonal Antibody

Catalog number ER1706-70

Price for ER1706-70

Size / count 100 µL

About this product

Cullin 3 is a protein that in humans is encoded by the CUL3 gene. Cullin 3 protein belongs to the family of cullins which in mammals contains eight proteins (Cullin 1, Cullin 2, Cullin 3, Cullin 4A, Cullin 4B, Cullin 5, Cullin 7 and Cullin 9). Cullin proteins are an evolutionarily conserved family of proteins throughout yeast, plants and mammals. Cullin 3 is a component of Cullin-RING E3 ubiquitin ligases complexes (CRLs) which are involved in protein ubiquitylation and represent a part of ubiquitin–proteasome system (UPS). Added ubiquitin moieties to the lysine residue by CRLs then target the protein for the proteasomal degradation. Cullin-RING E3 ubiquitin ligases are involved in many cellular processes responsible for cell cycle regulation, stress response, protein trafficking, signal transduction, DNA replication, transcription, protein quality control, circadian clock and development. Deletion of CUL3 gene in mice causes embryonic lethality.

Specifications

Catalog number: ER1706-70
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Product Name Alternative: CUL 3 antibody Cul-3 antibody cul3 antibody CUL3_HUMAN antibody Cullin-3 antibody Cullin3 antibody KIAA0617 antibody PHA2E antibody
Abbreviation: CUL-3, CUL3
Swiss Prot: Q13618 Human, Q9JLV5 Mouse
Cellular Locus: Golgi apparatus. Nucleus.
Host: Rabbit
Species Reactivity: Human, Mouse
Immunogen: Synthetic peptide within human Cullin-3 aa 724-768.
Isotype: IgG
Conjugation: Non-conjugated
Type: Rabbit polyclonal Antibody
Applications: WB, IHC-P, FC
Positive Control: SH-SY5Y, 293T, mouse testis tissue lysate, human kidney tissue, human placenta tissue.
Concentration: 1 mg/mL
Dilution: WB: 1:500-1:2,000 ;IHC-P: 1:50-1:500 ;FC: 1:50-1:100
Purity: Immunogen affinity purified.
Form: Liquid
Buffer: 1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight: Predicted band size: 89 kDa
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody: No

Frequently Asked Questions

What is the catalog number for Cullin-3 Rabbit Polyclonal Antibody?

The catalog number for Cullin-3 Rabbit Polyclonal Antibody is ER1706-70.

What sizes are available for Cullin-3 Rabbit Polyclonal Antibody?

Cullin-3 Rabbit Polyclonal Antibody is available in the following size(s): 100 µL.

Is Cullin-3 Rabbit Polyclonal Antibody in stock?

Cullin-3 Rabbit Polyclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

What is Cullin-3 Rabbit Polyclonal Antibody used for?

What is the molecular weight of the target protein?

Molecular weight information, where applicable, is listed on the datasheet under target details, useful for confirming the correct band on western blot.

How long will it take to receive this product if it’s custom made?

Lead times depend on the product type: custom polyclonal antibodies typically take 12-14 weeks, monoclonal antibodies 15-17 weeks, made-to-order recombinant proteins 4-8 weeks, and made-to-order recombinant antibodies 6-8 weeks. These are estimates and may shift due to production delays.

What is the recommended dilution for this antibody?

A recommended dilution range for each validated application is provided on the datasheet, but optimal dilution should be titrated for your specific experimental system, sample type, and detection method.