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Product details

PLGF Rabbit Polyclonal Antibody

Catalog number ER1706-88

Price for ER1706-88

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Size / count 100 µL

About this product

The onset of angiogenesis is believed to be an early event in tumorigenesis and may facilitate tumor progression and metastasis. Several growth factors with angiogenic activity have been described. These include fibroblast growth factor (FGF), platelet derived growth factor (PDGF), vascular endothelial growth factor (VEGF) and placenta growth factor (PlGF). Like VEGF, several PlGF variants have been shown to arise from alternative mRNA splicings. Evidence has suggested VEGF to be an obligatory component in PlGF signaling. While VEGF homodimers and VEGF/PlGF heterodimers function as potent mediators of mitogenic and chemotactic responses in endothelial cells, PlGF homodimers are effectual only at extremely high concentrations. Indeed, many of the physiological effects attributed to VEGF may actually be a result of VEGF/PlGF. VEGF and PlGF share a common receptor, Flt-1, and may also activate Flk-1/KDR.

Specifications

Catalog number
ER1706-88
Size / count
100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Product Name Alternative
D12S1900 antibody Pgf antibody PGFL antibody PIGF antibody Placenta growth factor antibody Placental growth factor antibody Placental growth factor, vascular endothelial growth factor related protein antibody PlGF 2 antibody PlGF antibody PLGF_HUMAN antibody PlGF2 antibody SHGC 10760 antibody
Abbreviation
PlGF, PGF, PGFL
Swiss Prot
P49763 Human, P49764 Mouse
Cellular Locus
Secreted.
Host
Rabbit
Species Reactivity
Human, Mouse
Immunogen
Recombinant protein within Human PLGF aa 11-161 / 221.
Isotype
IgG
Conjugation
Non-conjugated
Type
Rabbit polyclonal Antibody
Applications
IHC-P, FC
Positive Control
Human kidney tissue, mouse testis tissue, SH-SY5Y.
Concentration
1 mg/mL
Dilution
IHC-P: 1:50-1:200 ;FC: 1:50-1:100
Purity
Immunogen affinity purified.
Form
Liquid
Buffer
1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 25 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody
No

Frequently Asked Questions

What is the catalog number for PLGF Rabbit Polyclonal Antibody?

The catalog number for PLGF Rabbit Polyclonal Antibody is ER1706-88.

What sizes are available for PLGF Rabbit Polyclonal Antibody?

PLGF Rabbit Polyclonal Antibody is available in the following size(s): 100 µL.

Is PLGF Rabbit Polyclonal Antibody in stock?

PLGF Rabbit Polyclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

What is PLGF Rabbit Polyclonal Antibody used for?

The onset of angiogenesis is believed to be an early event in tumorigenesis and may facilitate tumor progression and metastasis. Several growth factors with angiogenic activity have been described. These include fibroblast growth factor (FGF), platelet derived growth factor (PDGF), vascular endothel

What is the recommended positive control for this assay?

A recommended positive control, where one is specified by the manufacturer, is listed on the datasheet or in the assay protocol.

How should this product be stored?

Storage conditions depend on the specific reagent and are listed on the product datasheet, with most antibodies and proteins requiring -20°C unless stated otherwise. It is your responsibility to store the product correctly immediately upon receipt; damage from improper storage after delivery is not eligible for replacement.

Is this product animal-origin-free?

Animal-origin-free status, where applicable, is noted on the datasheet under formulation details.

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