IL-17 Rabbit Polyclonal Antibody — image 1 of 3

Product details

IL-17 Rabbit Polyclonal Antibody

Catalog number ER1706-91

Price for ER1706-91

Size / count 100 µL

About this product

Cytokines are small, soluble proteins with pleiotropic effects on a variety of cell types. Cytokines have a regulatory function over the immune system and mediate aspects of inflammatory response. They exert their biological effects through the binding of membrane-bound receptors which, in turn, initiate signal transduction cascades and elicit physiological changes in their target cell. Interleukin-17 (IL-17) and its cognate receptor, IL-17R, are an example of such a cytokine receptor pair. Originally identified as a rodent cDNA termed CTLA8, IL-17 is capable of inducing the secretion of IL-6 and IL-8 and augmenting the expression of ICAM-1 in human fibroblast cultures. The IL-17 protein exhibits a striking degree of homology with the HSV13 protein which mimics its function. The IL-17 receptor is a type I transmembrane protein 864 amino acids in length, that is highly expressed in spleen and kidney.

Specifications

Catalog number: ER1706-91
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Product Name Alternative: CTLA 8 antibody CTLA-8 antibody CTLA8 antibody Cytotoxic T lymphocyte associated antigen 8 antibody Cytotoxic T lymphocyte associated protein 8 antibody Cytotoxic T lymphocyte associated serine esterase 8 antibody Cytotoxic T-lymphocyte-associated antigen 8 antibody IL 17A antibody IL-17 antibody IL-17A antibody IL17 antibody IL17_HUMAN antibody Il17a antibody Interleukin 17 (cytotoxic T lymphocyte associated serine esterase 8) antibody Interleukin 17A antibody Interleukin-17A antibody Interleukin17 antibody Interleukin17A antibody OTTHUMP00000016597 antibody OTTMUSP00000046003 antibody
Abbreviation: IL-17, IL-17A, CTLA-8, IL17A, CTLA8, IL17
Swiss Prot: Q16552 Human, Q61453 Rat
Cellular Locus: Secreted.
Host: Rabbit
Species Reactivity: Human
Immunogen: Synthetic peptide within Human IL-17 aa 60-109 / 155.
Isotype: IgG
Conjugation: Non-conjugated
Type: Rabbit polyclonal Antibody
Applications: WB, IHC-P, FC
Positive Control: Human tonsil tissue, Jurkat.
Concentration: 1 mg/mL
Dilution: WB: 1:500-1:2000 ;IHC-P: 1:1,000 ;FC: 1:50-1:100
Purity: Immunogen affinity purified.
Form: Liquid
Buffer: 1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight: Predicted band size: 18 kDa
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody: No

Frequently Asked Questions

What is the catalog number for IL-17 Rabbit Polyclonal Antibody?

The catalog number for IL-17 Rabbit Polyclonal Antibody is ER1706-91.

What sizes are available for IL-17 Rabbit Polyclonal Antibody?

IL-17 Rabbit Polyclonal Antibody is available in the following size(s): 100 µL.

Is IL-17 Rabbit Polyclonal Antibody in stock?

IL-17 Rabbit Polyclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

What is IL-17 Rabbit Polyclonal Antibody used for?

Does this cell line or biologic require a Material Transfer Agreement (MTA)?

Some products, including certain cell lines, plasmids, and tissue cultures, are subject to intellectual property terms and may require an MTA before we can ship. We’ll inform you in advance if this product requires one, and additional handling fees may apply.

What should I do if I need to report a performance issue with a specific lot of this product?

Provide the catalogue number, product name, lot number, and your experimental results to our technical support team. They’ll investigate and, if needed, escalate to the manufacturer, provided the product was used before expiry and stored correctly.

What is the isotype of this antibody?

Isotype information such as IgG1 or IgG2a is listed in the product specifications on the datasheet, relevant for selecting compatible detection reagents.