ADAM10 Rabbit Polyclonal Antibody — image 1 of 2

Product details

ADAM10 Rabbit Polyclonal Antibody

Catalog number ER1706-97

Price for ER1706-97

Size / count 100 µL

About this product

ADAM (a disintegrin and metalloprotease) proteins are a family of over 30 membrane-anchored, glycosylated, Zn2+ dependent proteases that are involved in cell-cell, cell-matrix interface related processes including fertilization, muscle fusion, secretion of TNFα (tumor necrosis factor α), and modulation of the neurogenic function of Notch and Delta. ADAM proteins possess a signal-domain, a pro-domain, a metalloprotease domain, a disintegrin domain (integrin ligand) a cysteine-rich region, an epidermal growth factor-like domain, a transmembrane domain and a cytoplasmic tail. ADAMs are expressed in brain, testis, epididymis, ovary, breast, placenta, liver, heart, lung, bone and muscle, and catalyze proteolysis, adhesion, fusion and intracellular signaling. ADAM10 is a TNF-processing enzyme that cleaves pro-TNF, a membrane-bound precusor protein, at Ala 76-Val 77, which causes membrane shedding of soluble TNF.

Specifications

Catalog number: ER1706-97
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Product Name Alternative: A disintegrin and metalloprotease domain 10 antibody A disintegrin and metalloproteinase domain 10 antibody AD 10 antibody AD10 antibody AD18 antibody ADA10_HUMAN antibody ADAM 10 antibody ADAM metallopeptidase domain 10 antibody ADAM10 antibody CD 156c antibody CD156c antibody CD156c antigen antibody CDw156 antibody disintegrin and metalloproteinase domain containing protein 10 antibody Disintegrin and metalloproteinase domain-containing protein 10 antibody HsT 18717 antibody HsT18717 antibody Kuz antibody Kuzbanian antibody Kuzbanian protein homolog antibody Kuzbanian, Drosophila, homolog of antibody MADM antibody Mammalian disintegrin metalloprotease antibody Mammalian disintegrin-metalloprotease antibody RAK antibody
Abbreviation: ADAM 10, ADAM10, KUZ, MADM
Swiss Prot: O14672 Human
Cellular Locus: Golgi apparatus, Plasma membrane, Cell junction, Cell membrane, Cell projection, Cytoplasm.
Host: Rabbit
Species Reactivity: Human
Immunogen: Recombinant protein within human ADAM10 aa 60-338.
Isotype: IgG
Conjugation: Non-conjugated
Type: Rabbit polyclonal Antibody
Applications: WB, IHC-P
Positive Control: SiHa, human prostate tissue.
Concentration: 1 mg/mL
Dilution: WB: 1:500-1:5,000 ;IHC-P: 1:50-1:200
Purity: Immunogen affinity purified.
Form: Liquid
Buffer: 1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight: Predicted band size: 84 kDa
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody: No

Frequently Asked Questions

What is the catalog number for ADAM10 Rabbit Polyclonal Antibody?

The catalog number for ADAM10 Rabbit Polyclonal Antibody is ER1706-97.

What sizes are available for ADAM10 Rabbit Polyclonal Antibody?

ADAM10 Rabbit Polyclonal Antibody is available in the following size(s): 100 µL.

Is ADAM10 Rabbit Polyclonal Antibody in stock?

ADAM10 Rabbit Polyclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

What is ADAM10 Rabbit Polyclonal Antibody used for?

Do you ship this product with dry ice?

Some products, including certain cell lines and biologics, require dry ice for transportation, which carries an additional fee shown clearly in your quotation. Dry ice delivery isn’t always possible to every destination due to transit time or local restrictions, so we check feasibility in advance and you must store the goods at the correct temperature the moment they arrive.

Is this product species cross-reactive?

Cross-reactivity data, based on available testing, is listed under the reactivity section of the datasheet. Contact us if you need reactivity confirmed for a species not listed.

Is there an additional fee for hazardous or dry ice shipping of this product?

Yes, if this product requires dry ice or is classed as hazardous for transport, the additional fee will be explicitly shown in your quotation before you confirm the order, so there are no surprise charges later.