PSMA Rabbit Polyclonal Antibody

About this product

Prostate cancer is the most frequently diagnosed cancer and the early detection of prostate cancer dramatically and efficiently reduces the observed mortality rate. Several proteins have been identified as specific markers of prostate cancer, and they may be useful as diagnostic indicators. PSA, prostate specific antigen, is the classical indicator for transformed prostate tissue; however, in addition to being upregulated in prostate cancer, PSA is also upregulated in non-malignant conditions, such as benign prostatic hyperplasia prostate. Conversely, STEAP (six-transmembrane epithelial antigen of the prostate), prostate carcinoma tumor antigen (PCTA-1) and prostate-specific membrane antigen (PSM) represent additional prostate-specific antigens that are overexpressed only in malignant tumors and therefore are more specific identifiers of malignancies. PSM is an integral membrane protein, and PCTA-1 is related to the galectin gene family, which mediate both cell-cell and cell-matrix interactions in a manner similar to the selectin subgroup of C-type lectins. STEAP is a serpentine transmembrane cell-surface tumor-antigen that is predicted to functions as a channel or transporter protein.

Specifications

Catalog number

ER1802-10

Size / count

100 µL

Dry ice

No

Hazardous

No

Discontinued

No

CAS Number

9007-83-4

Product Name Alternative

Cell growth inhibiting protein 27 antibody Cell growth-inhibiting gene 27 protein antibody FGCP antibody Folate hydrolase (prostate-specific membrane antigen) 1 antibody Folate hydrolase 1 antibody Folate hydrolase antibody Folate hydrolase prostate specific membrane antigen 1 antibody FOLH 1 antibody FOLH antibody Folh1 antibody FOLH1_HUMAN antibody Folylpoly gamma glutamate carboxypeptidase antibody Folylpoly-gamma-glutamate carboxypeptidase antibody GCP 2 antibody GCP II antibody GCP2 antibody GCPII antibody GIG27 antibody Glutamate carboxylase II antibody Glutamate carboxypeptidase 2 antibody Glutamate carboxypeptidase II antibody Membrane glutamate carboxypeptidase antibody mGCP antibody N acetylated alpha linked acidic dipeptidase 1 antibody N-acetylated-alpha-linked acidic dipeptidase I antibody NAALAD 1 antibody NAALAD1 antibody NAALAdase antibody NAALADase I antibody Prostate specific membrane antigen antibody Prostate specific membrane antigen variant F antibody Prostate-specific membrane antigen antibody PSM antibody PSMA antibody Pteroylpoly gamma glutamate carboxypeptidase antibody Pteroylpoly-gamma-glutamate carboxypeptidase antibody

Abbreviation

FGCP, GCPII, mGCP, NAALADase I, PSM, PSMA, FOLH1, FOLH, NAALAD1, PSM, PSMA, GIG27

Swiss Prot

Q04609 Human, O35409 Mouse, P70627 Rat

Cellular Locus

Cytoplasm, Cell membrane.

Host

Rabbit

Species Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide within Human PSMA aa 676-725 / 750.

Isotype

IgG

Conjugation

Non-conjugated

Type

Rabbit polyclonal Antibody

Applications

WB

Positive Control

LNCaP cell lysate, Mouse kidney tissue lysate, Rat kidney tissue lysate.

Concentration

1 mg/mL

Dilution

WB: 1:1,000

Purity

Immunogen affinity purified.

Form

Liquid

Buffer

1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.

Molecular Weight

Predicted band size: 84 kDa

Storage Conditions

Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Recombinant Antibody

No