Progesterone Receptor Rabbit Polyclonal Antibody — image 1 of 3

Product details

Progesterone Receptor Rabbit Polyclonal Antibody

Catalog number ER1802-19

Price for ER1802-19

Size / count 100 µL

About this product

The effects of progesterone are mediated by two functionally different isoforms of the progesterone receptor, PR-A and PR-B, which are transcribed from distinct, estrogen-inducible promoters within a single copy of the PR gene. The first 164 amino acids of PR-B are absent in PR-A. Progesterone-bound PR-A and PR-B have different transcription activation properties. Specifically, PR-B functions as a transcriptional activator in most cell and promoter contexts, while PR-A is transcriptionally inactive and functions as a strong ligand-dependent transdominant repressor of steroid hormone receptor transcriptional activity. An inhibitory domain (ID), which maps to the amino terminus of the receptor, exists within both PR isoforms. Interestingly, the ID is functionally active only in PR-A and is necessary for steroid hormone transrepression by PR-A, suggesting that PR-A and PR-B may have different conformations in the cell.

Specifications

Catalog number: ER1802-19
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Product Name Alternative: NR3C3 antibody Nuclear receptor subfamily 3 group C member 3 antibody PGR antibody PR antibody PRA antibody PRB antibody PRGR_HUMAN antibody Progesterone receptor antibody Progestin receptor form A antibody Progestin receptor form B antibody
Abbreviation: PR, PGR, NR3C3
Swiss Prot: P06401 Human, Q00175 Mouse
Cellular Locus: Cytoplasm. Nucleus.
Host: Rabbit
Species Reactivity: Human, Mouse
Immunogen: Synthetic peptide within N-terminal human Progesterone Receptor.
Isotype: IgG
Conjugation: Non-conjugated
Type: Rabbit polyclonal Antibody
Applications: IF-Cell, IHC-P
Positive Control: A549, Hela, MCF-7, human uterus tissue, mouse testis tissue.
Concentration: 1 mg/mL
Dilution: IF-Cell: 1:500-1:1,000;IHC-P: 1:100-1:500
Purity: Immunogen affinity purified.
Form: Liquid
Buffer: 1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight: 99 kDa
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody: No

Frequently Asked Questions

What is the catalog number for Progesterone Receptor Rabbit Polyclonal Antibody?

The catalog number for Progesterone Receptor Rabbit Polyclonal Antibody is ER1802-19.

What sizes are available for Progesterone Receptor Rabbit Polyclonal Antibody?

Progesterone Receptor Rabbit Polyclonal Antibody is available in the following size(s): 100 µL.

Is Progesterone Receptor Rabbit Polyclonal Antibody in stock?

Progesterone Receptor Rabbit Polyclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

What is Progesterone Receptor Rabbit Polyclonal Antibody used for?

What expression system was used for this recombinant protein?

The expression system, such as E. coli, HEK293, or insect cells, is listed on the datasheet under production details, which can affect post-translational modifications relevant to your application.

Can I return this product if I ordered the wrong one?

As a consumer, you have a 14-day right of withdrawal from receipt under EU consumer protection law, submitted via our withdrawal/cancellation request form. Note this applies to unused, undamaged products, and doesn’t override the expiry/storage conditions on performance-based claims.

Is this product tested for endotoxin levels?

Endotoxin testing status is noted on the datasheet where applicable, particularly for recombinant proteins intended for cell-based or functional assays. If this isn’t listed and you need confirmation, contact support with the catalogue number.